Home food changes and game-like impulse-control tools to help with weight

Evaluating environmental control (AVOID) and inhibitory control (RESIST) strategies to improve weight management outcomes

NIH-funded research Cedars-Sinai Medical Center · NIH-11293417

This project tests whether changing your home food environment and using game-like impulse-control training help adults with overweight or obesity lose more weight during a 12-month WW (Weight Watchers) program.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionCedars-Sinai Medical Center NIH-funded
Lab location1 site (Los Angeles, United States)
Project IDNIH-11293417 on NIH RePORTER

What this research studies

You would join a 12-month Weight Watchers (WW) program and 500 adults with BMI 25–39.9 will be randomly assigned to one of four groups. Some people will get only WW, others will get WW plus changes to their home food environment and online grocery delivery (AVOID), others will get WW plus a gamified impulse-control training app (RESIST), and a fourth group will get both additions. Staff who speak English and Spanish will collect weight, waist circumference, and diet-quality measures at baseline, 6 months, and 12 months to see which approach helps people lose more weight. The main goal is to compare weight loss and waist changes across groups, with diet quality as a secondary outcome.

Who could benefit from this research

Good fit: Adults with overweight or obesity (BMI 25–39.9 kg/m2) who are willing to join a 12-month WW program and can attend visits in the Los Angeles/Cedars‑Sinai area are ideal candidates.

Not a fit: People with BMI outside the 25–39.9 range, those who are pregnant, have recent bariatric surgery, or cannot participate in WW or use online delivery/apps are unlikely to benefit from this trial.

Why it matters

Potential benefit: If successful, these strategies could help people lose more weight and improve diet by making healthy choices easier and reducing impulsive eating.

How similar studies have performed: Behavioral weight-loss programs work best when people stick to them, and smaller studies suggest home food changes and inhibitory-control training can help, but combining these approaches in a large randomized trial is relatively new.

Where this research is happening

Los Angeles, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Adult-Onset Diabetes Mellitus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.