Recovery-oriented peer-led suicide prevention for people at high risk of psychosis
Official title: Development of a Recovery-Oriented Suicide Prevention Intervention with Peers for Clinical High Risk for Psychosis
Funded at University of California, San Diego · NIH-11357122 · Data updated 2026-11-12
A peer-supported program called RISE is being refined and tested to help people at high risk for psychosis stay engaged in care and reduce thoughts of suicide.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project start | June 5, 2026 |
| Project end | March 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $396,907 |
| NIH project number | 1R01MH144654-01 |
| Project ID | NIH-11357122 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults and young adults identified as clinical high risk for psychosis who are receiving routine mental health care and have elevated suicide risk.
✕Less likely to help
Individuals without elevated suicide risk or not in routine care may not benefit from this intervention.
What this research studies
This project adapts a proven peer-led intervention to the clinical high-risk for psychosis population and tests its preliminary effectiveness in real-world clinical settings. The study will use qualitative input from communities and advisory boards to refine the protocol, then open-label trial the intervention across two sites over three years. The program combines therapist and peer facilitation with four recovery-focused modules and caregiver guidance, plus cognitive strategies to help memory and application of what is learned. The research follows a hybrid type 1 design under the EPIS framework to balance effectiveness and implementation insights in routine care.
Why it matters
Potential benefit: If successful, the program could reduce suicide risk and increase engagement in care for people at high risk for psychosis.
How similar studies have gone: Prior peer-led and recovery-focused interventions have shown promise, but applying them specifically to CHR populations is an emerging area.
Where this research is happening
-
University of California, San Diego
La Jolla, United States Active
Researchers
- Principal investigator: Chalker, Samantha — University of California, San Diego
- Study coordinator: Chalker, Samantha
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.