Condition

Giant Cell Arteritis (GCA) clinical trials and research

• 14Clinical trials
• 7Countries

Newest Giant Cell Arteritis (GCA) clinical trials

All recruiting trials (14)

• Giant Cell Arteritis: Monitoring Disease Activity and Relapse Risk in Remission

  This study tests tools that help monitor disease activity and predict relapses in people with giant cell arteritis who are in remission.

  Recruiting at 4 sites University of Aarhus · Aalborg and 6 other locations · NCT07552636

• Combining vascular ultrasound and blood markers to improve diagnosis and monitoring of giant cell arteritis

  This project will test whether adding extended ultrasound scans to new blood biomarkers can better predict relapse and tell active from inactive giant cell arteritis in people referred for suspected GCA.

  Recruiting Vastra Gotaland Region · Gothenburg · NCT07246577

• Orbital blood-vessel inflammation in giant cell arteritis and ischemic optic neuropathy

  This project will test whether advanced FDG PET/MRI with black-blood sequences plus OCT scans can tell if sudden optic nerve damage is due to giant cell arteritis or non-arteritic ischemic optic neuropathy in people aged 50 and older.

  Recruiting Copenhagen University Hospital, Rigshospitalet · Glostrup Municipality · NCT07206238

• Personalized lab test to predict the best treatment for rheumatic diseases

  This project tests a lab-based cell assay to see if it can predict which DMARD will work best for adults with autoimmune rheumatic diseases such as RA, PsA, axSpA, and GCA.

  Recruiting University of Bonn · Bonn, North Rhine-Westphalia · NCT07150000

• Stopping versus reducing tocilizumab for people with well-controlled giant cell arteritis

  This trial will test whether stopping tocilizumab or reducing its dose better maintains remission in people with giant cell arteritis who have been on high-dose tocilizumab for at least 12 months and off steroids for at least three months.

  Recruiting at 7 sites Phase 2 National Institute of Allergy and Infectious Diseases (NIAID) · Atlanta, Georgia and 6 other locations · NCT07108387

• Halo sign in GCA: how soon after steroids to perform Doppler ultrasound

  This study tests whether timing of Doppler ultrasound after starting steroids affects the ability to see the halo sign in adults with giant cell arteritis.

  Recruiting at 4 sites Centre Hospitalier le Mans · Le Mans, Sarthe and 5 other locations · NCT07060274

• Optic nerve sheath ultrasound for diagnosing giant cell arteritis

  This will try using ultrasound to measure the optic nerve sheath to see if it helps diagnose giant cell arteritis in people over 50 with suspected GCA.

  Recruiting Hôpital NOVO · Aix-en-Provence and 8 other locations · NCT07001059

• Blocking endothelin to improve blood vessel function in large vessel vasculitis

  This study is testing if a medication called Bosentan can improve blood vessel function in people with large vessel vasculitis who have been in remission for at least six months.

  Recruiting Phase 2 University of Edinburgh · Edinburgh · NCT06887062

• Fast-track diagnosis for Giant Cell Arteritis

  This study is testing a new way to quickly diagnose Giant Cell Arteritis using ultrasound to see if it can help patients get the right treatment faster and avoid serious complications.

  Recruiting Groupe Hospitalier de la Rochelle Ré Aunis · La Rochelle · NCT06742671

• Investigating the Role of Y Chromosome Mutations in Autoimmune Diseases

  This study is trying to see how changes in the Y chromosome might affect the immune system and contribute to autoimmune diseases like Giant Cell Arteritis and Polymyalgia Rheumatica.

  Recruiting University of Bonn · Bonn, North Rhine-Westphalia · NCT06696027

• Evaluating Thrombomodulin for Ruling Out Giant Cell Arteritis in Patients with Polymyalgia Rheumatica

  This study is testing if a blood marker called thrombomodulin can help doctors tell if older patients with polymyalgia rheumatica also have giant cell arteritis.

  Recruiting Centre Hospitalier Universitaire Dijon · Dijon · NCT06609668

• Using Tocilizumab for treating aortitis in Giant Cell Arteritis

  This study is testing if a new version of Tocilizumab can safely help people with Giant Cell Arteritis and active aortitis feel better while they are already on standard treatment.

  Recruiting Groupe français d'étude des Maladies Inflammatoires de loeil · Paris · NCT06271018

• Exploring factors that predict treatment response in patients with polymyalgia rheumatica and giant cell arteritis

  This study is trying to find out what factors help predict how well new patients with polymyalgia rheumatica and giant cell arteritis will respond to steroid treatment.

  Recruiting University Hospital, Basel, Switzerland · Basel · NCT05479448

• Hydrocortisone vs. placebo for adrenal insufficiency symptoms after stopping glucocorticoids

  This study is testing if hydrocortisone can help people over 50 feel better after stopping glucocorticoids and dealing with adrenal insufficiency symptoms.

  Recruiting at 3 sites Phase 4 Odense University Hospital · Aarhus and 2 other locations · NCT05193396

Related topics

Quick answers

How many Giant Cell Arteritis (GCA) clinical trials are recruiting right now?

14, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in France (5 trials), Denmark (3 trials), Germany (2 trials), United Kingdom (1 trial), Switzerland (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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