Doctor screening versus questionnaire screening for psoriatic arthritis in people with psoriasis
Official title: Comparison of a Physician-Based Versus Questionnaire-Based Approach to Identify Patients With a High Probability of Psoriatic Arthritis Among Patients With Psoriasis: A Prospective Multicenter Study
Run by Charite University, Berlin, Germany · NCT07298265 · Data updated 2026-11-12
This study will test whether screening by a doctor or using short questionnaires finds more cases of psoriatic arthritis in adults with psoriasis.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | Charite University, Berlin, Germany Academic / other |
| Locations | 1 site (Toronto, Ontario) |
| Status | Recruiting |
| Started | September 22, 2025 |
| Main results expected | October 2026 |
| Study ends | October 2026 |
| Registry record updated | December 23, 2025 |
| Trial ID | NCT07298265 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (≥18) with a confirmed diagnosis of psoriasis who can give informed consent and who have not already been assessed by a rheumatologist (unless they have new musculoskeletal symptoms) are ideal candidates.
✕Probably not a fit
People under 18, those unable to consent, and patients who already had a rheumatology assessment for PsA with no new symptoms are unlikely to benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Researchers will compare physician-conducted screening to several validated questionnaire tools (PASE, ToPAS/TOPAS 2, PEST, EARP) in adults with confirmed psoriasis seen at participating dermatology clinics. Eligible participants are adults (≥18) with a definite diagnosis of psoriasis who have not been previously evaluated by a rheumatologist unless new musculoskeletal symptoms have developed. The observational design involves administering questionnaires alongside routine physician screening and documenting subsequent rheumatology referrals and diagnostic outcomes. The study aims to determine which approach identifies more previously unrecognized cases of psoriatic arthritis and could shorten diagnostic delay.
Why it matters
Potential benefit: If successful, this could help diagnose psoriatic arthritis earlier and reduce joint damage and long-term disability.
How similar studies have gone: Several questionnaires for PsA screening have been developed and validated and have shown usefulness in finding undiagnosed cases, though accuracy varies and direct head-to-head comparisons with physician screening remain limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age \>= 18 years. 2. Definite diagnosis of psoriasis. 3. Written informed consent. Exclusion Criteria: 1. Unable or unwilling to give informed consent or to comply with the protocol. 2. Previously assessed by a rheumatologist for the presence of PsA, unless new musculoskeletal symptoms have emerged subsequent to the prior evaluation.
Where it's running
-
University Health Network / University Of Toronto
Toronto, Ontario, Canada Recruiting
Study contacts
- Study coordinator: Denis Poddubnyy, MD, PhD, MsC, Professor
- Email: Denis.Poddubnyy@uhn.ca
- Phone: +1416603 5753
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.