Condition

Psoriasis (PsO) clinical trials and research

• 18Clinical trials
• 13Countries

Newest Psoriasis (PsO) clinical trials

All recruiting trials (18)

• Retinal Vessel Density and Foveal Avascular Zone Size in Psoriatic Arthritis

  This study tests whether retinal blood vessel density and the size of the foveal avascular zone differ between people with psoriatic arthritis, people with psoriasis, and healthy individuals using non-invasive eye imaging.

  Recruiting Bursa Yuksek Ihtisas Training and Research Hospital · Bursa, Yıldırım · NCT07858591

• Is XJH05 Ointment Effective for Plaque Psoriasis?

  This study tests whether the XJH05 ointment can help people with plaque psoriasis compare to a calcipotriol ointment.

  Recruiting Xijing Hospital · Xi'an, Shaanxi · NCT07780929

• HL40626S tablets in healthy adults: a first-in-human dose study

  This Phase 1 study tests HL40626S tablets in healthy adults to see if it is safe, tolerated, and how it behaves in the body after single and 14-day multiple doses.

  Recruiting Phase 1 HighsLab Therapeutics Inc. · Melbourne, Victoria and 1 other locations · NCT07736586

• Global psoriasis care patterns and outcomes (observational)

  This study tests how psoriasis is managed across different health systems by following patients over time to see care access, treatments, disease severity, and quality of life.

  Recruiting University of Zurich · Zurich · NCT07634016

• S-4321 in adults with autoimmune or immune-mediated diseases

  This study tests S-4321 in adults with autoimmune conditions to see if it is safe and tolerable and to gather early data on how the drug behaves in the body and its initial effects on disease markers.

  Recruiting at 2 sites Phase 1 Seismic Therapeutic AU Pty Ltd · Charlestown, New South Wales and 1 other locations · NCT07455578

• Semaglutide plus topical steroid/calcipotriol for plaque psoriasis in adults with overweight, obesity, or type 2 diabetes

  This trial will test whether taking oral semaglutide along with a topical steroid/calcipotriol cream improves skin symptoms and reduces metabolic inflammation in adults with plaque psoriasis who are overweight, obese, or have type 2 diabetes.

  Recruiting Phase 4 Hospital Universitario Dr. Jose E. Gonzalez · Monterrey, N.L. · NCT07401992

• Audio-based therapy to help anxiety in people with psoriasis

  This study tests whether a short audio therapy session can ease anxiety in adults with psoriasis.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07390487

• Tildrakizumab for symptoms and quality of life in Canadians with moderate-to-severe plaque psoriasis (Fitzpatrick III+)

  This study will test how tildrakizumab affects symptoms, safety, and quality of life in adults in Canada with moderate-to-severe plaque psoriasis who are starting treatment through the ILUMYA SUPPORT® Program and have Fitzpatrick skin types III or higher.

  Recruiting at 7 sites Chronicle Academy · Burlington, Ontario and 6 other locations · NCT07370766

• Doctor screening versus questionnaire screening for psoriatic arthritis in people with psoriasis

  This study will test whether screening by a doctor or using short questionnaires finds more cases of psoriatic arthritis in adults with psoriasis.

  Recruiting Charite University, Berlin, Germany · Toronto, Ontario · NCT07298265

• Oral roflumilast treatment for adults with moderate-to-severe plaque psoriasis

  This 12-week pilot will try daily oral roflumilast to see if it safely reduces psoriasis symptoms in adults with moderate-to-severe plaque psoriasis.

  Recruiting Phase 2 Mansoura University Hospital · Al Mansurah, Dakahlia Governorate · NCT07233291

• Probiotics plus methotrexate in early psoriasis

  This test will see if taking daily probiotics along with weekly methotrexate helps adults with newly diagnosed psoriasis have better skin outcomes and healthier gut bacteria than taking methotrexate alone.

  Recruiting Early Phase 1 Alexandria University · Alexandria · NCT07169019

• Molecular Inflammation Board for personalized care of chronic inflammatory diseases

  This project collects clinical, lab, imaging, and patient-reported data from adults with psoriasis, psoriatic arthritis, spondyloarthritis, or inflammatory bowel disease who are referred to the Molecular Inflammation Board to see if the board's recommendations influence care and outcomes.

  Recruiting University Hospital Tuebingen · Tübingen · NCT07132333

• SKINERGY: deep biomarker profiling of immune-driven skin diseases in dermatology clinics

  This project will test whether detailed blood, tissue, imaging, and patient-reported biomarker profiles in adults with several immune-related skin conditions can find patterns that distinguish disease types and predict who responds to treatment.

  Recruiting Leiden University Medical Center · Nijmegen, Gelderland and 7 other locations · NCT07021495

• Deucravacitinib safety during pregnancy.

  This project will see if taking deucravacitinib during pregnancy affects pregnancy and baby outcomes for people with psoriasis.

  Recruiting Bristol-Myers Squibb · La Jolla, California · NCT07017699

• Assessing the effects of IL-17 inhibitors on hidden inflammation in psoriasis patients

  This study is testing if IL-17 inhibitors can help reduce hidden inflammation in adults with moderate to severe psoriasis who aren't getting enough relief from their current treatments.

  Recruiting at 2 sites The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School · Nanjing, Jiangsu and 1 other locations · NCT06987292

• LPX-TI641 safety and body handling in people with atopic dermatitis or psoriasis.

  This trial will test whether taking LPX-TI641 by mouth for 28 days is safe and how the drug behaves in the body for adults with atopic dermatitis or psoriasis.

  Recruiting at 3 sites Phase 1 LAPIX Therapeutics Inc. · Fargo, North Dakota and 2 other locations · NCT06982352

• Using semaglutide to treat psoriasis in obese patients

  This study is testing if the weight loss drug semaglutide can help improve psoriasis symptoms in adults who are both obese and have psoriasis.

  Recruiting Phase 3 The University of Hong Kong · Hong Kong · NCT06937060

• Public reactions to facial psoriasis, atopic dermatitis, vitiligo, and alopecia areata

  This project tests how adults in the general population emotionally and socially respond to faces showing psoriasis, atopic dermatitis, vitiligo, or alopecia areata.

  Recruiting Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Roma, Italia · NCT06801821

Related topics

Quick answers

How many Psoriasis (PsO) clinical trials are recruiting right now?

18, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 13 countries. The most sites are in United States (3 trials), Egypt (2 trials), Australia (2 trials), Canada (2 trials), China (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 3, Early Phase 1: 1, Phase 2: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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