Oxidative stress in autoimmune joint diseases

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational project will enroll adults with rheumatoid arthritis, psoriatic arthritis, or ankylosing spondylitis at the General University Hospital of Larissa. Biological samples (such as blood) and clinical information on disease status, treatments, comorbidities, diet and physical activity will be collected. Laboratory assays will measure oxidative stress and antioxidant markers and statistical analyses will look for patterns and correlations with disease type, severity, comorbidity and therapy. No experimental treatments are given; the work aims to deepen understanding of molecular changes associated with these conditions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult patients (\>18 years old), with a primary diagnosis of rheumatoid arthritis using the criteria of American College of Rheumatology (ACR)
* Adult patients (\>18 years old), with a primary diagnosis of psoriatic arthritis using the ClASsification criteria for Psoriatic Arthritis (CASPAR)
* Adult patients (\>18 years old), with a primary diagnosis of alkylosing spondyloarthritis using the criteria of Assessment of SpondyloArthritis international Society (ASAS) group
* Adult patients (\>18 years old) irrespective of gender
* Adult patients (\>18 years old) irrespective of ethnicity
* Adult patients (\>18 years old) irrespective of comorbidities
* Adult patients (\>18 years old) irrespective of socioeconomic background
* Adult patients (\>18 years old) with any disease status
* Adult patients (\>18 years old) with any disease duration
* Adult patients (\>18 years old) under any treatment scheme (e.g. non-steroidal anti-inflammatory drugs, steroids, disease-modifying anti-rheumatic drugs including biologics)

Exclusion Criteria:

* Adult patients (\>18 years old) with concurrent infectious disease
* Adult patients (\>18 years old) in pregnancy
* Patients under 18 years of age

Where it's running

• General University Hospital of Larissa. Greece
  Larissa, Thessaly, Greece Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.