Examining MRI Features to Improve Prostate Cancer Diagnosis
Official title: Exploring the Correlation Between MRI Image Characteristics and Diagnosis, Pathology and Prognosis in Patients With Prostate Lesions
Run by Tongji Hospital · NCT06946771 · Data updated 2026-11-12
This study is trying to see if special MRI pictures can help doctors better diagnose prostate cancer in men with high PSA levels or abnormal exams, aiming to reduce unnecessary biopsies and improve patient care.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | Men only |
| Enrollment | 500 (estimated) |
| Sponsor | Tongji Hospital Academic / other |
| Drugs / interventions | chemotherapy, radiation |
| Locations | 1 site (Wuhan, Hubei) |
| Status | Recruiting |
| Started | February 25, 2025 |
| Main results expected | December 1, 2027 |
| Study ends | December 31, 2028 |
| Registry record updated | April 27, 2025 |
| Trial ID | NCT06946771 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adult males with elevated PSA levels or abnormal findings on digital rectal examinations.
✕Probably not a fit
Patients who have already undergone prostate biopsy or other anti-tumor treatments may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to explore the relationship between MRI image characteristics and the diagnosis, pathology, and prognosis of prostate lesions in patients. It focuses on men with elevated prostate-specific antigen (PSA) levels or abnormal digital rectal examinations, utilizing advanced multiparametric MRI techniques to enhance the accuracy of prostate cancer detection. By analyzing MRI data, the study seeks to reduce unnecessary biopsies and improve patient outcomes. Participants will be recruited from Tongji Hospital in Wuhan, China.
Why it matters
Potential benefit: If successful, this study could lead to more accurate prostate cancer diagnoses and reduce the number of unnecessary biopsies for patients.
How similar studies have gone: Previous studies have shown that multiparametric MRI can significantly improve the detection rate of prostate cancer, indicating a promising approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Patients with abnormal prostate-specific antigen (PSA) elevated (\>4.0 ng/ml) or abnormal digital rectal examination (DRE) or suspicious lesions found by prostate ultrasound, CT or MRI in the hospital 2. Age/Gender: Adult male 3. Patients who voluntarily participate in clinical trials and sign a written informed consent form for subjects Exclusion Criteria: 1. Patients with pacemakers, unknown materials, metal implants in the body, neurostimulators, and claustrophobia 2. Patients who underwent biopsy, local ablation, prostate surgery, or endocrine therapy, chemotherapy, radiotherapy and other anti-tumor treatments before examination
Where it's running
-
Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology
Wuhan, Hubei, China Recruiting
Study contacts
- Study coordinator: Zhen Li
- Email: zhenli@hust.edu.cn
- Phone: 02783663543
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.