Clinical trial Recruiting at 1 site Observational Ages 18 and up Men only

Examining MRI Features to Improve Prostate Cancer Diagnosis

Official title: Exploring the Correlation Between MRI Image Characteristics and Diagnosis, Pathology and Prognosis in Patients With Prostate Lesions

Run by Tongji Hospital · NCT06946771 · Data updated 2026-11-12

This study is trying to see if special MRI pictures can help doctors better diagnose prostate cancer in men with high PSA levels or abnormal exams, aiming to reduce unnecessary biopsies and improve patient care.

Quick facts

Study typeObservational
Ages18 Years and up
SexMen only
Enrollment500 (estimated)
SponsorTongji Hospital
Academic / other
Drugs / interventionschemotherapy, radiation
Locations1 site (Wuhan, Hubei)
StatusRecruiting
StartedFebruary 25, 2025
Main results expectedDecember 1, 2027
Study endsDecember 31, 2028
Registry record updatedApril 27, 2025
Trial IDNCT06946771 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adult males with elevated PSA levels or abnormal findings on digital rectal examinations.

Probably not a fit

Patients who have already undergone prostate biopsy or other anti-tumor treatments may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore the relationship between MRI image characteristics and the diagnosis, pathology, and prognosis of prostate lesions in patients. It focuses on men with elevated prostate-specific antigen (PSA) levels or abnormal digital rectal examinations, utilizing advanced multiparametric MRI techniques to enhance the accuracy of prostate cancer detection. By analyzing MRI data, the study seeks to reduce unnecessary biopsies and improve patient outcomes. Participants will be recruited from Tongji Hospital in Wuhan, China.

Why it matters

Potential benefit: If successful, this study could lead to more accurate prostate cancer diagnoses and reduce the number of unnecessary biopsies for patients.

How similar studies have gone: Previous studies have shown that multiparametric MRI can significantly improve the detection rate of prostate cancer, indicating a promising approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Patients with abnormal prostate-specific antigen (PSA) elevated (\>4.0 ng/ml) or abnormal digital rectal examination (DRE) or suspicious lesions found by prostate ultrasound, CT or MRI in the hospital
2. Age/Gender: Adult male
3. Patients who voluntarily participate in clinical trials and sign a written informed consent form for subjects

Exclusion Criteria:

1. Patients with pacemakers, unknown materials, metal implants in the body, neurostimulators, and claustrophobia
2. Patients who underwent biopsy, local ablation, prostate surgery, or endocrine therapy, chemotherapy, radiotherapy and other anti-tumor treatments before examination

Where it's running

  • Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology
    Wuhan, Hubei, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.