Condition

Hot Flashes clinical trials and research

• 20Clinical trials
• 2NIH research projects
• 7Countries

Newest Hot Flashes clinical trials

All recruiting trials (20)

• Plant extract supplement for menopausal symptoms in women around menopause

  A plant-extract dietary supplement is being tested to see if it helps hot flashes and related symptoms in women aged 42–60 who are nearing or just past menopause, compared with a placebo.

  Recruiting University of Alicante · Elche, Alicante · NCT07863973

• Shatavari-based herbal extract to help menopausal symptoms

  This study tests whether an 8-week daily herbal extract containing Shatavari can reduce menopausal symptoms in postmenopausal women, compared with a placebo.

  Recruiting India Glycols Ltd · New Port Richey, Florida · NCT07834463

• Can fezolinetant reduce hot flashes for Indian women going through menopause

  This study tests whether fezolinetant can lessen hot flashes and night sweats in Indian menopausal women who have persistent vasomotor symptoms.

  Recruiting Phase 3 Astellas Pharma Inc · Bengaluru, Karnataka · NCT07829653

• Wearable cooling device to ease hot flashes in men on ADT for prostate cancer

  A randomized test to see if the Embr Wave wearable can reduce hot flashes in men with prostate cancer on androgen deprivation therapy.

  Recruiting Dana-Farber Cancer Institute · Boston, Massachusetts · NCT07729150

• Fezolinetant use for menopausal hot flashes in Canada

  This observational study in Canada follows women with menopausal vasomotor symptoms who are taking fezolinetant in routine care to see how well it helps after 12 weeks and over a year.

  Recruiting at 2 sites Astellas Pharma Inc · Montreal and 1 other locations · NCT07602530

• Acupuncture vs Sham Acupuncture for Hot Flashes in Prostate Cancer on Hormone Therapy

  This study tests whether real acupuncture can reduce hot flashes and improve quality of life in men with prostate cancer who are on hormone therapy.

  Recruiting University of Kentucky · Lexington, Kentucky · NCT07594002

• Use of a smartwatch to track hot flashes in men receiving androgen deprivation therapy

  This project will try using a smartwatch to record hot flashes and other health signals in men with prostate cancer on androgen deprivation therapy and compare those records with daily survey reports.

  Recruiting University of Virginia · Charlottesville, Virginia · NCT07535541

• Acupuncture to ease hot flashes in men on hormone therapy for prostate cancer

  This trial will test if weekly acupuncture plus lifestyle education can help reduce hot flashes and related symptoms in men receiving androgen deprivation therapy for prostate cancer.

  Recruiting Inova Health Care Services · Fairfax, Virginia · NCT07335224

• JDS-HF3.0 supplement to ease menopause symptoms in postmenopausal women

  This trial will see if taking two JDS-HF3.0 tablets each morning for 12 weeks can reduce hot flashes, night sweats, and joint discomfort in postmenopausal women aged 50–70.

  Recruiting Bonafide Health · Harrison, New York · NCT07238478

• Fezolinetant to reduce hot flashes in men on androgen-deprivation therapy

  This trial will test whether taking fezolinetant once daily for 4 weeks reduces how often and how severe hot flashes are in men with prostate cancer who are on androgen-deprivation therapy.

  Recruiting Phase 2 Brigham and Women's Hospital · Boston, Massachusetts · NCT06957691

• Fezolinetant to reduce hot flashes in men on androgen-deprivation therapy

  This trial will test whether taking fezolinetant once daily for 4 weeks reduces how often and how severe hot flashes are in men with prostate cancer who are on androgen-deprivation therapy.

  Recruiting Phase 2 Brigham and Women's Hospital · Boston, Massachusetts · NCT06957691

• Evaluating the effects of GABA on menopause symptoms

  This study is testing if a GABA supplement can help menopausal women feel better by reducing symptoms like hot flashes, sleep problems, and mood swings.

  Recruiting Ospedale Policlinico San Martino · Genova, Italia · NCT06864520

• Breathing muscle training to help midlife women with menopause symptoms

  This study is testing if breathing exercises can help women aged 45-60 feel better during menopause by reducing hot flashes and improving sleep quality.

  Recruiting Mayo Clinic · Rochester, Minnesota · NCT06743269

• Using Shatavari to treat menopausal symptoms in women

  This study is testing if Shatavari can help women aged 45 to 65 feel better during menopause by reducing symptoms like hot flashes and mood swings.

  Recruiting SF Research Institute, Inc. · San Francisco, California · NCT06716554

• Virtual registry for menopause and perimenopause in Australia

  This study is creating an online registry to collect information from Australian women about their experiences with menopause and perimenopause to help improve healthcare and support for them.

  Recruiting Bespoke Clinical Research · Adelaide · NCT06487130

• Exercise to Reduce Hot Flushes in Postmenopausal Women

  This study is testing whether strength training or high-intensity aerobic exercise can help reduce hot flushes in postmenopausal women.

  Recruiting at 2 sites Linkoeping University · Kalmar and 1 other locations · NCT06030388

• Comparing Lemborexant, Zopiclone, and Clonidine for treating insomnia in chronic pain patients

  This study is testing whether Lemborexant, Zopiclone, or Clonidine can help people with chronic pain sleep better and manage their pain.

  Recruiting Salem Anaesthesia Pain Clinic · Surrey, British Columbia · NCT05618002

• Examining the cardiovascular effects of hot flushes in postmenopausal women

  This study tests how hot flushes affect heart and breathing responses in postmenopausal women to see if symptoms and body fat impact these effects.

  Recruiting University of Minnesota · Minneapolis, Minnesota · NCT05251324

• Investigating hot flashes and their impact on women's vascular health

  This study is testing how hot flashes might affect women's heart and blood vessel health, especially during menopause, to see if they increase the risk of high blood pressure and heart disease.

  Recruiting Mayo Clinic · Rochester, Minnesota · NCT05193968

• Comparing solifenacin and clonidine for treating hot flashes in breast cancer patients

  This study tests whether solifenacin can help reduce hot flashes in women with breast cancer undergoing hormonal therapy, comparing it to clonidine to see which works better.

  Recruiting Phase 2 University of Arkansas · Little Rock, Arkansas · NCT01530373

NIH-funded research (2)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Investigating hot flashes and blood vessel function in women

  This study is looking at how hot flashes during menopause might impact blood vessel health in women, and it’s for women who experience different levels of hot flashes to help us understand their heart health better as they get older.

  NIH research Mayo Clinic Rochester · Rochester, United States · NIH-11075859

• Using PhytoSERM to help manage menopausal hot flashes and support brain health.

  This study is looking at how a new treatment called PhytoSERM can help relieve menopausal symptoms like hot flashes and support brain health in women going through menopause, offering a safer option than traditional hormone therapy.

  NIH research Neutherapeutics, LLC · Tucson, United States · NIH-10707107

Related topics

Quick answers

How many Hot Flashes clinical trials are recruiting right now?

20, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in United States (13 trials), Canada (2 trials), Sweden (1 trial), Italy (1 trial), Spain (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 3, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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