Condition

Androgen Deprivation Therapy clinical trials and research

• 10Clinical trials
• 7NIH research projects
• 3Countries

Newest Androgen Deprivation Therapy clinical trials

All recruiting trials (10)

• Understanding how ADT for prostate cancer may raise blood pressure and whether nerves or kidneys are involved

  This study tests whether nervous system or kidney dysfunction contributes to high blood pressure in men receiving androgen deprivation therapy for prostate cancer.

  Recruiting Phase 4 Virginia Commonwealth University · Richmond, Virginia · NCT07848828

• Radiotherapy after prostate removal for node-positive prostate cancer

  This study tests whether adding pelvic radiotherapy to ongoing hormone therapy helps men with node-positive prostate cancer after prostate removal live longer without cancer progression.

  Recruiting at 5 sites Phase 3 Sun Yat-sen University · Dongguan, Guangdong and 12 other locations · NCT07477626

• Acupuncture to ease hot flashes in men on hormone therapy for prostate cancer

  This trial will test if weekly acupuncture plus lifestyle education can help reduce hot flashes and related symptoms in men receiving androgen deprivation therapy for prostate cancer.

  Recruiting Inova Health Care Services · Fairfax, Virginia · NCT07335224

• Home-based telerehabilitation for rural men on hormone therapy for metastatic prostate cancer

  This trial tests whether a home telerehabilitation program helps men in rural areas receiving androgen deprivation therapy for metastatic prostate cancer feel and function better than home exercise without the technology.

  Recruiting University of Utah · Salt Lake City, Utah · NCT07032584

• Fezolinetant for hot flashes in men receiving androgen-deprivation therapy

  This test will try whether fezolinetant reduces hot flashes in men with prostate cancer who get them from androgen deprivation therapy.

  Recruiting Phase 2 University of Vermont · Burlington, Vermont · NCT06972875

• Fezolinetant to reduce hot flashes in men on androgen-deprivation therapy

  This trial will test whether taking fezolinetant once daily for 4 weeks reduces how often and how severe hot flashes are in men with prostate cancer who are on androgen-deprivation therapy.

  Recruiting Phase 2 Brigham and Women's Hospital · Boston, Massachusetts · NCT06957691

• Fezolinetant to reduce hot flashes in men on androgen-deprivation therapy

  This trial will test whether taking fezolinetant once daily for 4 weeks reduces how often and how severe hot flashes are in men with prostate cancer who are on androgen-deprivation therapy.

  Recruiting Phase 2 Brigham and Women's Hospital · Boston, Massachusetts · NCT06957691

• Combining relugolix and enzalutamide for high-risk prostate cancer treatment

  This study is testing if combining two medications, relugolix and enzalutamide, can help men with high-risk prostate cancer do better with their treatment and live longer.

  Recruiting Phase 1 University of Oklahoma · Oklahoma City, Oklahoma · NCT06130995

• Comparing short and long-term hormone therapy with radiation for prostate cancer

  This study tests whether short-term or long-term hormone therapy combined with radiation is better for men with prostate cancer who have had a recurrence after surgery.

  Recruiting at 6 sites Phase 3 Instituto de Investigación en Oncología Radioterápica - Fundación Española de Oncología Radioterápic · L'Hospitalet de Llobregat, Barcelona and 16 other locations · NCT05781217

• Exercise program to improve heart health in Black men with prostate cancer on hormone therapy

  This study is testing whether a special exercise program can help improve heart health and overall well-being in Black men with prostate cancer who are receiving hormone therapy.

  Recruiting Dana-Farber Cancer Institute · Boston, Massachusetts · NCT05327465

NIH-funded research (7)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Lineage changes in cancer cells drive resistance to radiation and hormone therapy

  A cancer-focused study looks at how a mitochondrial enzyme modification may cause tumor cells to resist radiation and hormone therapy in prostate cancer.

  NIH research University of Cincinnati · Cincinnati, United States · NIH-11540492

• Molecular tests to predict long-term response to hormone therapy and radiation for prostate cancer

  This project looks for molecular signs in tumor samples that could show which men with prostate cancer returning after surgery will benefit most from hormone therapy plus radiation.

  NIH research Washington University · Saint Louis, United States · NIH-11248810

• Investigating how changes in mitochondrial function affect cancer resistance to treatments.

  This study is looking at how changes in a key protein in our cells might help cancer cells survive treatments like radiation and hormone therapy, and it hopes to find a way to make these treatments more effective for patients whose cancers are hard to treat.

  NIH research University of Texas Hlth Science Center · San Antonio, United States · NIH-11042247

• Identifying biomarkers to improve prostate cancer treatment outcomes after surgery.

  This study is looking at how certain biological markers can help doctors figure out which men with prostate cancer, who have had surgery, will respond best to hormone therapy and radiation, so they can personalize treatments for better results.

  NIH research Washington University · Saint Louis, United States · NIH-11003668

• Using exercise to lower heart disease risk in men receiving hormone therapy for prostate cancer

  This study is looking at how exercise can help men with prostate cancer who are receiving hormone therapy stay healthier and lower their chances of heart problems, by testing easy home workout programs that can improve their fitness and heart health.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-10913604

• How hormone therapy affects blood pressure and kidney function in men

  This study is looking at how hormone therapy for prostate cancer affects blood pressure and kidney health in men, aiming to find ways to help manage blood pressure better during treatment.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-10897020

• Effects of long-term hormone therapy on brain function in prostate cancer patients

  This study is looking at how long-term hormone therapy for prostate cancer might affect thinking and memory skills in patients, with the hope of finding ways to improve their quality of life and treatment choices.

  NIH research Yale University · New Haven, United States · NIH-10666534

Related topics

Quick answers

How many Androgen Deprivation Therapy clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 3 countries. The most sites are in United States (8 trials), Spain (1 trial), China (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 3, Phase 3: 2, Phase 1: 1, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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