Observational study of men with advanced prostate cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study collects biological samples and health information from men diagnosed with advanced prostate cancer to better understand the disease and improve future treatment outcomes. Participants will provide blood and urine samples, complete surveys, and have their medical records reviewed. The primary goal is to create a biorepository that can be used for further research into prostate cancer. This observational approach allows researchers to gather real-world data on treatment responses and quality of life.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Men of all racial and ethnic groups 18 years of age or older
* Men with a diagnosis of advanced (metastatic) prostate cancer who are scheduled to begin a new systemic treatment (including first or subsequent lines of therapy)
* Prior participation on clinical trials is allowed

Exclusion Criteria:

* Inability to give informed consent
* Any other malignancy, unless previously treated with curative intent and the subject has been disease free for 3 years or longer

Where it's running

• Los Angeles General Medical Center
  Los Angeles, California, United States Recruiting
• USC / Norris Comprehensive Cancer Center
  Los Angeles, California, United States Recruiting

Study contacts

• Principal investigator: Amir Goldkorn, MD — University of Southern California
• Study coordinator: Cheryl Kefauver, RN
• Email: Cheryl.Kefauver@med.usc.edu
• Phone: 323-865-0459

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Understanding NK Cell Function in Prostate Cancer Across Races

  This study tests whether natural killer (NK) cells behave differently in prostate cancer patients of diverse racial backgrounds by analyzing blood and tissue samples.

  Recruiting Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT07910019

• MRI or CT planning to guide high-dose-rate prostate brachytherapy

  This trial tests whether adding an MRI to CT-based treatment planning for HDR prostate brachytherapy changes urinary side effects in men with localized prostate cancer.

  Recruiting at 3 sites Emory University · Atlanta, Georgia and 2 other locations · NCT07859722

• Targeted Early Detection for Men at High Genetic Risk for Prostate Cancer

  This study tests urinary biomarkers and PSA to see if they can improve early detection for men with a strong family or genetic risk for prostate cancer.

  Recruiting University of Michigan Rogel Cancer Center · Ann Arbor, Michigan · NCT07645391

• Urine and MRI approach to find aggressive prostate cancer early

  This study tests whether a urine test called MPS2, paired with MRI, can better detect aggressive prostate cancer in men 50–75 at risk, possibly reducing unnecessary biopsies.

  Recruiting University of Michigan Rogel Cancer Center · Ann Arbor, Michigan · NCT07526545

• GET FIT Together: a socially enhanced exercise program for older men with prostate cancer

  This program tests whether adding structured social support to supervised online exercise reduces cancer-related loneliness and improves mental and physical health in men 65 and older who have had prostate cancer.

  Recruiting OHSU Knight Cancer Institute · Portland, Oregon · NCT07504835

• Improved MRI methods to distinguish benign from cancerous pelvic findings

  This test tries new deep-learning image-processing methods on MRI scans to get clearer images faster for adults scanned for prostate screening or suspected endometriosis.

  Recruiting Mayo Clinic · Rochester, Minnesota · NCT07407959

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.