Observational study of men with advanced prostate cancer

Longitudinal Advanced Prostate Cancer Cohort (LAPCC)

University of Southern California · NCT06067295

This study is collecting blood, urine, and health information from men with advanced prostate cancer to help researchers learn more about the disease and improve future treatments.

Quick facts

Study typeObservational
Enrollment300 (estimated)
Ages18 Years and up
SexMale
SponsorUniversity of Southern California (other)
Locations2 sites (Los Angeles, California and 1 other locations)
Trial IDNCT06067295 on ClinicalTrials.gov

What this trial studies

This study collects biological samples and health information from men diagnosed with advanced prostate cancer to better understand the disease and improve future treatment outcomes. Participants will provide blood and urine samples, complete surveys, and have their medical records reviewed. The primary goal is to create a biorepository that can be used for further research into prostate cancer. This observational approach allows researchers to gather real-world data on treatment responses and quality of life.

Who should consider this trial

Good fit: Ideal candidates are men aged 18 and older with a diagnosis of advanced prostate cancer who are about to start a new systemic treatment.

Not a fit: Patients who are unable to give informed consent will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved treatment strategies and outcomes for patients with advanced prostate cancer.

How similar studies have performed: Other observational studies have successfully contributed to understanding advanced prostate cancer, making this approach both relevant and valuable.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Men of all racial and ethnic groups 18 years of age or older
* Men with a diagnosis of advanced (metastatic) prostate cancer who are scheduled to begin a new systemic treatment (including first or subsequent lines of therapy)
* Prior participation on clinical trials is allowed

Exclusion Criteria:

* Inability to give informed consent
* Any other malignancy, unless previously treated with curative intent and the subject has been disease free for 3 years or longer

Where this trial is running

Los Angeles, California and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Prostate Carcinoma

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.