Improving prostate cancer classification using MRI and AI
Official title: Integrating Quantitative MRI and Artificial Intelligence to Improve Prostate Cancer Classification
Run by Jonsson Comprehensive Cancer Center · NCT04765150 · Data updated 2026-11-12
This study is testing whether using advanced MRI scans and artificial intelligence can help doctors better identify and classify prostate cancer.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | Men only |
| Enrollment | 275 (estimated) |
| Sponsor | Jonsson Comprehensive Cancer Center Academic / other |
| Locations | 1 site (Los Angeles, California) |
| Status | Recruiting |
| Started | April 1, 2021 |
| Main results expected | June 1, 2027 |
| Study ends | June 1, 2028 |
| Registry record updated | July 7, 2026 |
| Trial ID | NCT04765150 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include male patients aged 18 and older with a clinical suspicion or biopsy-confirmed prostate cancer who are undergoing multi-parametric 3T MRI.
✕Probably not a fit
Patients with contraindications to MRI or gadolinium contrast agents, or those who have received prior radiotherapy, may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the integration of advanced magnetic resonance imaging (MRI) techniques and artificial intelligence to enhance the accuracy of prostate cancer diagnosis. It aims to develop quantitative analysis methods that reduce variability in MRI results and improve the detection of clinically significant prostate cancer. The study involves both retrospective review of medical records and prospective MRI imaging sessions at UCLA. By utilizing multi-class deep learning models, the research seeks to systematically analyze MRI features for better classification of prostate cancer.
Why it matters
Potential benefit: If successful, this study could lead to more accurate and less invasive diagnostic techniques for prostate cancer.
How similar studies have gone: Other studies have shown promise in using advanced imaging and AI for cancer diagnosis, indicating a potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Male patients 18 years of age and older * Clinical suspicion of prostate cancer or biopsy-confirmed prostate cancer * Undergone or undergoing multi-parametric 3 T prostate MRI at the University of California at Los Angeles (UCLA) * Ability to provide consent Exclusion Criteria: * Contraindications to MRI (e.g., cardiac devices, prosthetic valves, severe claustrophobia) * Contraindications to gadolinium contrast-based agents other than the possibility of an allergic reaction to the gadolinium contrast-based agent * Prior radiotherapy
Where it's running
-
UCLA / Jonsson Comprehensive Cancer Center
Los Angeles, California, United States Recruiting
Study contacts
- Principal investigator: Kyung H Sung, PhD — UCLA / Jonsson Comprehensive Cancer Center
- Study coordinator: Nashla Barroso
- Email: nbarroso@mednet.ucla.edu
- Phone: (310) 794-7952
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.