Condition

Oral Health clinical trials and research

• 12Clinical trials
• 81NIH research projects
• 11Countries

Newest Oral Health clinical trials

All recruiting trials (12)

• Can mouth health and chewing help explain arterial stiffness in healthy adults

  This study tests whether a profile of oral health and function adds information about central arterial stiffness beyond traditional risk factors in healthy adults.

  Recruiting VASCage GmbH · Innsbruck, Tyrol · NCT07736222

• Large language models for turning structured dental radiology data into narrative reports

  This study tests whether a language model can convert organized dental X‑ray findings into clear, complete radiology reports.

  Recruiting Hospital of the Ministry of Interior, Kielce, Poland · Kielce, Świętokrzyskie Voivodeship · NCT07676318

• Turkish Oral Assessment Sheet for checking mouth health in older adults.

  This project will test whether the Turkish version of the Oral Assessment Sheet works well for people aged 60 and older to check lips, tongue, saliva, swallowing, and voice.

  Recruiting Necmettin Erbakan University · Konya, Konya · NCT07507864

• Oral health knowledge in pregnant women: does a one-time information leaflet help?

  A one-time printed leaflet is tested to see if it improves oral health knowledge in pregnant women attending Hospital La Fe.

  Recruiting University of Valencia · Valencia, Valencia · NCT07413393

• Oral signs to help spot eating disorders early

  This project will test whether a standardized checklist of mouth and dental signs can help detect eating disorders in adults aged 18–40 during routine dental visits.

  Recruiting University of Bologna · Bologna · NCT07295197

• Examining the link between oral health and delirium in surgical patients

  This study is trying to see if better oral health can help prevent delirium in patients having heart or lung surgery.

  Recruiting Xinhua Hospital, Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT06969092

• Effects of dietary nitrate supplements on oral health

  This study tests if taking beetroot juice or beetroot crystals can improve oral health for healthy adults by looking at things like saliva and mouth bacteria.

  Recruiting Newcastle University · Newcastle · NCT06956612

• Using mouthguards to prevent dental injuries in sports

  This study tests if custom mouthguards can help prevent dental injuries in athletes aged 7 to 30 while also looking at how well they accept wearing them and how it affects their oral health.

  Recruiting Universidade Federal do Rio de Janeiro · Rio de Janeiro, Rio de Janeiro · NCT06912451

• Evaluating oral health among students at the University of São Paulo

  This study looks at the oral health of current and former students at the University of São Paulo to see how it affects their academic performance and attendance over five years.

  Recruiting University of Sao Paulo · São Paulo · NCT06853639

• Understanding how diet affects health in older adults in Auvergne-Rhône-Alpes

  This study looks at how what older adults eat affects their health to help create personalized diet plans for people aged 55 to 75 living in the Auvergne-Rhône-Alpes region.

  Recruiting Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement · Meylan, Isere and 1 other locations · NCT06695780

• Evaluating an oil rinse product for dental health

  This study is testing whether using an oil rinse called PerioPull™ can improve dental health in adults over 12 weeks.

  Recruiting Designs for Health · Ellicott City, Maryland · NCT06363721

• Preventing pressure ulcers, malnutrition, poor oral health, and falls in older adults receiving municipal health care

  This study is testing a new program to help prevent pressure ulcers, malnutrition, poor oral health, and falls in older adults living in nursing homes by training staff on better care practices.

  Recruiting Malmö University · Malmö · NCT05308862

NIH-funded research (newest 40 of 81)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Coordinated Oral Health Promotion for Chicago Kids

  A long-running study in Chicago is following children and their caregivers to find ways to reduce tooth decay and improve daily life for families.

  NIH research University of Illinois at Chicago · Chicago, UNITED STATES · NIH-11614800

• Digital adolescent dental health program to reduce tooth decay in at-risk youth

  A digital program designed for lower-income 7th and 8th graders to help them avoid tobacco use and sugary drinks to lower the risk of tooth decay.

  NIH research Oregon Research Institute · Springfield, UNITED STATES · NIH-11520407

• Improving how schools deliver tooth care for kids using existing data

  This project analyzes past school-based dental care data to help more underserved children get effective, affordable preventive treatment.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11477436

• Host genetics and oral microbiome: big-data clues to oral health

  A large study will combine human genetics, saliva bacteria, and health records to understand why oral diseases like cavities and gum disease occur in different people.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11438184

• Understanding dry mouth in adults using AI to read electronic records

  A new project uses AI to find adults with xerostomia in medical records and predict who will have worse oral health outcomes.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11437326

• Oral health effects of buprenorphine and methadone in people with opioid use disorder

  This project will explore how common MOUD medicines like buprenorphine (including dissolvable forms) and methadone may affect oral health in people with opioid use disorder.

  NIH research Chestnut Health Systems, INC. · Bloomington, United States · NIH-11427115

• Innovative methods for next-generation evidence synthesis in oral health

  A research project to improve how we collect, combine, and interpret dental research so guidelines and care decisions are faster and more accurate.

  NIH research University of Arizona · Tucson, United States · NIH-11419690

• EC16 Nanoparticles for preventing Alzheimer’s risk linked to gum disease

  A tiny, edible nanoparticle treatment from Camellix aims to reduce gum infection and may help lower the risk of developing Alzheimer's disease in older adults.

  NIH research Camellix, LLC · Evans, United States · NIH-11404985

• Understanding how sublingual buprenorphine affects oral health in adults with opioid use disorder

  This grant explores whether taking sublingual buprenorphine for opioid use disorder can change the mouth’s health, and what that means for people who rely on this treatment.

  NIH research University of Kentucky · Lexington, United States · NIH-11394629

• Behavioral program to improve kids’ oral health around dental surgery

  A CHW-delivered parenting program helps families of children who need dental surgery to reduce sugary foods and improve brushing to prevent future tooth decay.

  NIH research University of Illinois at Chicago · Chicago, UNITED STATES · NIH-11392693

• Silver Diamine Fluoride and Medicaid Policy to Improve Kids’ Tooth Health

  A government-funded study will look at how Medicaid policies around silver diamine fluoride affect dental care and outcomes for children ages 0-11.

  NIH research Ohio State University · Columbus, UNITED STATES · NIH-11391303

• Developing a Collaborative Dental Practice-Based Research Network to Advance Health Equity

  A nationwide dental education project partners two universities to build a practice-based research network that focuses on reducing racial disparities in dental care.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11374841

• PRIMED: Training the next generation of clinical oral health researchers

  A program to train clinicians and researchers so they can turn dental research into real improvements in oral health.

  NIH research University of the Pacific-Stockton · Stockton, United States · NIH-11374523

• Miniaturized high-frequency ultrasound imaging for oral health in head and neck diseases

  A small, ultra-high-frequency ultrasound device will be developed and tested to image gums and teeth more clearly, helping people with periodontal disease and other mouth problems.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11370038

• Better access to high‑quality dental care for all Americans

  This grant aims to improve how dental care is accessed and used across the population by combining patient experiences, provider input, and population data.

  NIH research Utah State Higher Education System--University of Utah · Salt Lake City, United States · NIH-11365236

• Oral Health and Dementia Subtypes: How Mouth Health Might Influence Alzheimer’s and Vascular Dementia

  A large NIH grant is exploring whether and how oral health problems like gum disease and tooth loss relate to different forms of dementia, using big datasets and biological markers.

  NIH research New York University · New York, United States · NIH-11362506

• Oral health trends in US nursing homes

  A short-project that uses nursing home data to see how older adults in care facilities are faring with tooth decay and gum disease.

  NIH research Univ of Massachusetts Med Sch Worcester · Worcester, United States · NIH-11356424

• Oral Health Microsimulation for Older Adults

  A computer-based model will help forecast how aging, access to care, and social factors affect dental health and costs for adults 65 and older in the U.S.

  NIH research University of Chicago · Chicago, United States · NIH-11356270

• How sublingual buprenorphine may affect mouth and dental health

  This project will compare saliva, mouth bacteria, and dental health in adults with opioid use disorder who take sublingual buprenorphine to learn whether the medicine is linked to more oral disease.

  NIH research University of Kentucky · Lexington, United States · NIH-11354406

• Impact of Reduced-Exposure Nicotine Products on Mouth Health for High-Risk Adults

  This project looks at how using reduced-exposure nicotine products might affect oral health in adults at high risk for mouth diseases.

  NIH research Roswell Park Cancer Institute Corp · Buffalo, United States · NIH-11354055

• Multi-Level Interventions to Reduce Oral Health Disparities in Primary Care

  A research project tests simple, real-world changes in primary care to help low-income adults improve their oral health and visit a dentist more often.

  NIH research Case Western Reserve University · Cleveland, United States · NIH-11327307

• How financial stress and opportunities shape oral health in young adults

  Researchers will track people moving from adolescence into adulthood to see how money, schooling, work, and behavior affect their dental and overall health.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11314586

• MOLAR: Connecting ED patients to oral health care and local resources

  This project tests simple, patient-friendly ways to connect people who visit the emergency department for dental problems with nearby dental clinics and information so they can get ongoing oral care.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11309693

• Personalized app and smart brushing support to improve adult oral hygiene

  A personalized Android app paired with a smart brushing tracker to help adults stick to better tooth-brushing routines.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11309684

• Seniors’ Oral Health in Alaska: Understanding tooth disease outcomes in Alaska Native elders

  A long-term study will track older Alaska Native and American Indian adults to understand how dental disease progresses and what helps keep gums and teeth healthier.

  NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11309675

• Mothers Action Project to improve young children's dental health and nutrition

  This project offers a year-long neighborhood group program to help South Asian mothers change feeding and tooth-care habits for 1–5 year-olds to lower tooth decay and unhealthy weight.

  NIH research Univ of Massachusetts Med Sch Worcester · Worcester, United States · NIH-11307180

• Preventing tooth decay in Alaska Native infants and young children

  This project helps families in Yukon‑Kuskokwim communities get coordinated dental care and practical prevention tips to stop tooth decay in infants and preschoolers.

  NIH research Alaska Native Tribal Health Consortium · Anchorage, United States · NIH-11259559

• Closing tooth decay gaps for children with data-driven risk tools

  This project uses computer-based risk models to find which young children—especially those on Medicaid or from Black and Hispanic communities—are most likely to get serious tooth decay so programs can target help.

  NIH research Harvard Medical School · Boston, United States · NIH-11239028

• Help for families to prevent repeat cavities after children's dental surgery

  This project offers coaching by community health workers to help parents of preschool children who had dental surgery improve toothbrushing and cut back on sugary foods.

  NIH research University of Illinois at Chicago · Chicago, UNITED STATES · NIH-11195717

• Improving Oral Health for All Americans

  This project aims to find better ways to provide high-quality dental care and improve oral health for all Americans.

  NIH research Utah State Higher Education System--University of Utah · Salt Lake City, United States · NIH-11192770

• Understanding Oral Health: Stress, Habits, and Neighborhood Factors

  This project explores how daily stress, lifestyle choices, and where people live affect the oral health of adults, especially those of Central and South American heritage.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11190922

• How economic factors affect oral health in young adults

  This study looks at how money troubles and opportunities affect young people's oral health as they move from being teenagers to adults, especially focusing on those who might be facing tougher challenges, to find the best ways to help them keep their smiles healthy.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11158860

• Improving Dental Care for All through a New Research Network

  This project aims to create a new research network within dental schools to help address health differences and improve dental care for diverse communities.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11158838

• CATCH Healthy Smiles: An Oral Health Program for Elementary School Children

  This program helps kindergarten through second-grade children learn healthy habits to prevent cavities in school.

  NIH research University of Texas Hlth Sci Ctr Houston · Houston, United States · NIH-11144582

• Improving oral health behaviors in children undergoing dental surgery

  This study is all about helping kids from low-income and minority families take better care of their teeth after they've had dental surgery, by teaching their parents how to encourage good brushing habits and cut down on sugar, with support from friendly community health workers.

  NIH research University of Illinois at Chicago · Chicago, UNITED STATES · NIH-11139943

• Using a smartphone app to improve oral health habits

  This study is testing a new app called eBrush that helps people improve their tooth-brushing habits by giving personalized tips and support, making it easier for everyone to take better care of their teeth.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11129631

• Coordinated oral health support for Chicago families with young children

  This project tries to help parents of young Chicago children improve toothbrushing habits and reduce tooth decay using community health workers and home-based support.

  NIH research University of Illinois at Chicago · Chicago, UNITED STATES · NIH-11128652

• Understanding the Connection Between Gum Disease and Alzheimer's

  This research explores if gum disease might increase the risk of memory problems and Alzheimer's disease in older adults.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11126701

• Improving child health and oral health through social networks

  This study is testing a program called the Mothers Action Project (MAP) to help low-income immigrant families, especially South Asian moms, make healthier choices about feeding their young kids and taking care of their teeth, all while building a supportive community over a year to reduce the risk of cavities and obesi

  NIH research Univ of Massachusetts Med Sch Worcester · Worcester, United States · NIH-11126562

• Improving oral health care for low-income older adults in primary care settings

  This study is looking to help older adults with low incomes in Northeast Ohio take better care of their teeth by bringing dental health support into their regular doctor visits, making it easier for them to get the care they need.

  NIH research Case Western Reserve University · Cleveland, United States · NIH-11103396

Related topics

Quick answers

How many Oral Health clinical trials are recruiting right now?

12, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 11 countries. The most sites are in Brazil (2 trials), Turkey (Türkiye) (1 trial), China (1 trial), Italy (1 trial), Poland (1 trial). Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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