Impact of Reduced-Exposure Nicotine Products on Mouth Health for High-Risk Adults
Official title: Impact of Reduced-Exposure Nicotine Product Use on Oral Health Conditions among the High-Risk Population
Funded at Roswell Park Cancer Institute Corp · NIH-11354055 · Data updated 2026-11-12
This project looks at how using reduced-exposure nicotine products might affect oral health in adults at high risk for mouth diseases.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Roswell Park Cancer Institute Corp NIH-funded |
| Lab location | 1 site (Buffalo, United States) |
| Project start | July 8, 2026 |
| Project end | July 7, 2028 |
| Funding year | 2026 |
| Award (this year) | $347,000 |
| NIH project number | 1R03DE036072-01 |
| Project ID | NIH-11354055 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults 21+ who are at high risk for oral health conditions and use or have used tobacco products.
✕Less likely to help
Individuals without tobacco exposure or those not at risk for oral health conditions may see no direct benefit.
What this research studies
This grant explores whether switching to reduced-exposure nicotine products changes oral health outcomes at the population level for adults who are already at high risk. Researchers will use national data to compare oral health conditions among those who use reduced-exposure products, traditional tobacco, or have quit, considering time since quitting. The study builds on existing data about tobacco- and nicotine-product use and aims to clarify potential benefits for oral tissues such as the cheek and buccal mucosa. The results could inform future guidance on safer nicotine options and their role in preventing oral diseases associated with tobacco use.
Why it matters
Potential benefit: If successful, findings could help people understand whether switching to reduced-exposure nicotine products may lower the risk of oral health problems.
How similar studies have gone: Existing evidence links quitting tobacco to better oral health, but population-level effects of reduced-exposure products are less clear and may be novel.
Where this research is happening
-
Roswell Park Cancer Institute Corp
Buffalo, United States Active
Researchers
- Principal investigator: Kasza, Karin a — Roswell Park Cancer Institute Corp
- Study coordinator: Kasza, Karin a
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.