NIH-funded research U01 cooperative agreement

Preventing tooth decay in Alaska Native infants and young children

Official title: Early Intervention for Childhood Caries to Address Alaska Native Disparities in Oral Health

Funded at Alaska Native Tribal Health Consortium · NIH-11259559 · Data updated 2026-11-12

This project helps families in Yukon‑Kuskokwim communities get coordinated dental care and practical prevention tips to stop tooth decay in infants and preschoolers.

More Oral Health research and trials

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionAlaska Native Tribal Health Consortium
NIH-funded
Lab location1 site (Anchorage, United States)
Project startApril 12, 2024
Project endJanuary 31, 2029
Funding year2026
Award (this year)$422,513
NIH project number5U01DE033642-03
Project IDNIH-11259559 on NIH RePORTER

Who could benefit from this research

Could help

Alaska Native infants and children under 6 years old in the Yukon‑Kuskokwim region, especially those under 24 months or with limited access to dental care, are the intended participants.

Less likely to help

Children who live outside the Yukon‑Kuskokwim communities or older children who already had full‑mouth dental reconstructions are less likely to benefit from this program.

What this research studies

You and your child will be supported by community health aides and dental health aide therapists who coordinate care and deliver practical prevention counseling like toothbrushing, fluoride, and reducing sugary drinks. The program brings dental interventions to children before 24 months and links services across about 50 remote communities through a single Tribal Health Organization. Parents will receive education and providers will work together so problems are caught early and treated locally when possible. The goal is to reduce severe early childhood caries and avoid full‑mouth dental reconstruction under general anesthesia.

Why it matters

Potential benefit: Could lower rates of severe early childhood tooth decay, reduce the need for dental surgery under anesthesia, and improve children's sleep, eating, and school performance.

How similar studies have gone: Care‑coordination, fluoride use, and parent education have reduced early childhood caries in other settings, but this program applies those approaches in remote Alaska Native communities.

Where this research is happening

  • Alaska Native Tribal Health Consortium
    Anchorage, United States
    Active

Researchers

  • Principal investigator: Thomas, Timothy K — Alaska Native Tribal Health Consortium
  • Study coordinator: Thomas, Timothy K

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.