Examining the link between oral health and delirium in surgical patients
Official title: A Study on the Correlation Between Oral Health and Delirium in Surgical Inpatients
Run by Xinhua Hospital, Shanghai Jiao Tong University School of Medicine · NCT06969092 · Data updated 2026-11-12
This study is trying to see if better oral health can help prevent delirium in patients having heart or lung surgery.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 90 Years |
| Sex | All |
| Enrollment | 550 (estimated) |
| Sponsor | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Shanghai, Shanghai Municipality) |
| Status | Recruiting |
| Started | May 25, 2025 |
| Main results expected | March 25, 2026 |
| Study ends | March 25, 2026 |
| Registry record updated | May 13, 2025 |
| Trial ID | NCT06969092 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients aged 18 years and older scheduled for elective cardiac or thoracic surgery requiring endotracheal intubation.
✕Probably not a fit
Patients with pre-existing oral conditions or those who have undergone certain treatments like radiotherapy or chemotherapy prior to surgery may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study investigates the relationship between oral health and the occurrence of delirium in surgical inpatients, particularly focusing on those undergoing elective cardiac or thoracic surgery. It aims to identify how oral frailty may contribute to the onset of postoperative delirium, a common and serious complication in hospitalized patients. By analyzing the oral health status of patients before and after surgery, the study seeks to establish correlations that could inform preventive strategies. The findings could lead to improved patient outcomes and reduced healthcare costs associated with delirium.
Why it matters
Potential benefit: If successful, this study could enhance the understanding of how oral health impacts postoperative delirium, potentially leading to better prevention strategies for at-risk patients.
How similar studies have gone: While the relationship between oral health and various health outcomes has been explored, this specific correlation with delirium in surgical patients is relatively novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged ≥18 years scheduled for elective cardiac or thoracic surgery requiring endotracheal intubation. Patients without consciousness impairment, able to cooperate with the investigation. Patients or their legal guardians informed about the study's purpose, methodology, and content, with signed informed consent forms. Exclusion Criteria: * Patients with pre-existing oral conditions (e.g., xerostomia, oral mucosal lesions) prior to mechanical ventilation. Patients with a history of radiotherapy, chemotherapy, or corticosteroid use before surgery. Patients experiencing intraoperative mortality.
Where it's running
-
Shanghai Xinhua hospital
Shanghai, Shanghai Municipality, China Recruiting
Study contacts
- Study coordinator: Aimin Shao, master
- Email: 1224103064@qq.com
- Phone: 18796080248
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.