Intensive lifestyle changes after AF ablation in people who are overweight

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized trial enrolls adults with paroxysmal or persistent atrial fibrillation scheduled for catheter ablation at National Taiwan University Hospital. All participants receive standard ablation and guideline-based AF care, then are randomized to either an intensive lifestyle modification program or usual care. The intervention includes dietary counseling for weight loss and a supervised aerobic plus resistance training program, with home-based activity recommendations. Data collected will include clinical and procedural information, rhythm follow-up, biological samples, and imaging metrics to explore links between lifestyle changes, adipose biology, gut microbiota, and post-ablation outcomes. The study aims to determine whether lifestyle modification improves outcomes in obese AF patients undergoing ablation.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with Class I indication of catheter ablation of paroxysmal or persistent AF and will undergo catheter ablation at National Taiwan University Hospital.

Exclusion Criteria:

1. Informed consent could not be obtained due to personal problem
2. Unwillingness or inability to return for follow-up visits or reason to believe that adherence to follow-up visits wound be irregular
3. Current or scheduled enrollment in other conflicting studies, and
4. Concomitant disease or other medical condition likely to result in death within 6 months

Where it's running

• National Taiwan University Hospital
  Taipei, Taiwan Recruiting

Study contacts

• Study coordinator: Yen Bin, Liu Associate Professor of Medicine, MD, PhD
• Email: yenbin@ntu.edu.tw
• Phone: +886-0972651035

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.