Condition

Myositis clinical trials and research

• 11Clinical trials
• 14NIH research projects
• 26Countries

Newest Myositis clinical trials

All recruiting trials (11)

• Imaging markers for bulbar involvement in inclusion body myositis among IBM and comparison groups

  This study tests whether ultrasound and MRI can detect swallowing and bulbar muscle problems in people with inclusion body myositis.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT07823101

• CR-402 treatment for refractory autoimmune disease

  This study tests CRT-402, a CD19-targeted CAR-T therapy, in adults with active, treatment-resistant autoimmune diseases like SLE, systemic sclerosis, and inflammatory myopathy to see if it is safe and capable of helping control disease.

  Recruiting Phase 1/2 Myeloid Therapeutics · Nedlands, Western Australia · NCT07778446

• Treatment Response in Myositis-Associated RP-ILD in Adults

  This study tests how people with myositis and rapidly progressing interstitial lung disease respond to an immunosuppressant treatment approach.

  Recruiting Singapore General Hospital · Singapore · NCT07775235

• Measuring muscle health with a handheld electrical impedance device (mScan)

  This project will test whether a handheld mScan device can quickly measure muscle health in adults with myopathies and in people without muscle disease by comparing its readings to MRI.

  Recruiting Beth Israel Deaconess Medical Center · Boston, Massachusetts · NCT07502989

• Patient-rooted insights to shape myositis science

  This global project asks people living with myositis (and their care partners) to share experiences and rank research questions so the community can see which issues matter most.

  Recruiting Myositis International Health & Research Collaborative Alliance Foundation · New Orleans, Louisiana · NCT07374107

• AlloNK® therapy combined with rituximab for treating certain autoimmune diseases

  This study is testing if a new treatment called AlloNK® combined with rituximab can help people with tough-to-treat autoimmune diseases feel better.

  Recruiting at 52 sites Phase 2 Artiva Biotherapeutics, Inc. · Tuscaloosa, Alabama and 51 other locations · NCT06991114

• Evaluating CTX112 for treating refractory autoimmune diseases in adults

  This study is testing a new CAR T cell treatment called CTX112 to see if it can help adults with tough autoimmune diseases like lupus and scleroderma feel better.

  Recruiting at 16 sites Phase 1 CRISPR Therapeutics · La Jolla, California and 16 other locations · NCT06925542

• Evaluating a new questionnaire for myositis patients

  This study is testing a new questionnaire to see how well it helps understand the physical and emotional challenges faced by people with myositis.

  Recruiting Hacettepe University · Ankara, Altındağ · NCT06587724

• Understanding how PF-06823859 works in patients with muscle inflammation disorders

  This study is testing a new medication called PF-06823859 to see if it can help adults with muscle inflammation disorders like dermatomyositis and polymyositis feel better compared to a placebo.

  Recruiting at 125 sites Phase 3 Pfizer · Glendale, Arizona and 137 other locations · NCT05895786

• Collection of biological samples to study systemic autoimmune diseases

  This study is collecting samples from people with autoimmune diseases like lupus and scleroderma to see if they can find new ways to diagnose and treat these conditions better.

  Recruiting University Hospital, Toulouse · Toulouse · NCT05251415

• Investigating environmental factors linked to anti-synthetase syndrome

  This study is trying to see if certain environmental factors, like infections or other triggers, might play a role in causing anti-synthetase syndrome in people with myositis.

  Recruiting at 2 sites National Institutes of Health Clinical Center (CC) · Miami, Florida and 7 other locations · NCT01276470

NIH-funded research (14)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Myositis-ILD Risk Prediction: How ILD Progresses in Myositis Patients

  A study to build better tools that predict how lung disease linked to myositis will behave in diverse patients.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11416500

• Autoantibodies and membrane repair in myositis

  A blood and tissue study seeks to understand how immune reactions against muscle repair proteins contribute to inflammatory myositis, with the goal of guiding better treatments for people with this condition.

  NIH research Ohio State University · Columbus, UNITED STATES · NIH-11381103

• Why chikungunya causes long-lasting joint and muscle pain

  This work looks at how chikungunya virus can linger in joint and muscle cells and keep causing pain for people who had the infection.

  NIH research Washington University · Saint Louis, United States · NIH-11325369

• Autoantibodies against muscle membrane repair proteins in myositis

  This work looks at whether people with myositis have antibodies that attack proteins that fix damaged muscle cell membranes and how that may cause muscle inflammation and weakness.

  NIH research Ohio State University · Columbus, UNITED STATES · NIH-11196770

• Predicting lung disease outcomes in people with myositis

  This project combines medical information and genetic markers to predict which people with myositis will have worsening interstitial lung disease.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11193816

• Cancer risk in inflammatory muscle disease (myositis)

  This project looks for signs in people with idiopathic inflammatory myopathies that show whether they have or might develop cancer.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11174212

• Understanding how Chikungunya virus causes long-lasting joint and muscle pain

  This study is looking into how the Chikungunya virus can cause long-lasting joint and muscle pain in some people, and it aims to find out how the virus sticks around in the body so we can develop better treatments for those who are suffering.

  NIH research Washington University · Saint Louis, United States · NIH-11112490

• Understanding how NT5c1A antibodies affect muscle disease in older adults

  This study is looking at how a specific antibody might affect the progression of sporadic inclusion body myositis (sIBM) in older adults, by tracking changes in muscle and blood over two years to help us better understand the disease and improve future treatments.

  NIH research University of California-Irvine · Irvine, United States · NIH-11081760

• Understanding swallowing and airway function in sporadic inclusion body myositis

  This study is looking at how sporadic inclusion body myositis affects swallowing and breathing functions, especially since problems with swallowing can lead to serious issues like pneumonia, and it's for people with this condition to help understand their challenges better.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-10997659

• Investigating autoantibodies related to muscle repair in myositis

  This study is looking at how certain proteins that help repair muscle cells might affect the muscle weakness and inflammation seen in idiopathic inflammatory myopathies, with the hope of finding better treatments for people dealing with these challenging conditions.

  NIH research Ohio State University · Columbus, UNITED STATES · NIH-10945787

• Predicting risks and outcomes for lung disease in myositis patients

  This study is looking to help people with interstitial lung disease linked to myositis by finding better ways to predict how their condition will progress, using information from different patients and their genes, so that doctors can provide the right level of care for everyone, no matter where they live.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-10883025

• Understanding the link between cancer and muscle diseases

  This study is looking at how muscle weakness from idiopathic inflammatory myopathies (IIM) might be linked to a higher risk of cancer, and it hopes to find specific markers in the blood that could help predict cancer in people with IIM, making cancer screenings easier and more effective for patients like you.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-10855717

• Investigating how T cells affect muscle disease in inclusion body myositis

  This study is looking at how certain immune cells called T cells might affect muscle loss in people with sporadic inclusion body myositis (IBM), and it hopes to find new ways to help manage the disease by understanding these cells better.

  NIH research University of California-Irvine · Irvine, United States · NIH-10797018

• Developing a new gene therapy for treating muscle degeneration in older adults

  This study is testing a new gene therapy called AVGN7 to help older adults with sporadic inclusion body myositis (IBM) by boosting muscle strength and function, with hopes of making life easier and more enjoyable for those living with this challenging condition.

  NIH research Aavogen, INC. · Rockville, United States · NIH-10709907

Related topics

Quick answers

How many Myositis clinical trials are recruiting right now?

11, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 26 countries. The most sites are in United States (7 trials), Germany (3 trials), Spain (3 trials), France (3 trials), Turkey (Türkiye) (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 1, Phase 1/2: 1, Phase 3: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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