Condition

Microbial Colonization clinical trials and research

• 24Clinical trials
• 6NIH research projects
• 14Countries

Newest Microbial Colonization clinical trials

All recruiting trials (24)

• Bile acid and gut microbiota changes in people with hepatitis D starting bulevirtide

  This project will see if starting bulevirtide changes bile acids and gut bacteria in adults with chronic hepatitis D who are already on hepatitis B therapy.

  Recruiting Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Roma · NCT07429864

• Nasal microbiota transplant to restore infant nasal microbiome after intranasal mupirocin

  This trial will try a parent-to-child nasal microbiota transplant to see if it restores nasal microbial diversity in newborns after intranasal mupirocin treatment for S. aureus.

  Recruiting Phase 1 Johns Hopkins University · Baltimore, Maryland · NCT06805994

• Exploring how visiting green areas affects the human microbiome

  This study is testing whether spending time in green spaces can change the bacteria on our skin and in our noses for both kids and adults.

  Recruiting Universiteit Antwerpen · Antwerp · NCT06574724

• Effects of Haskap Berries on Gut Health and Metabolism

  This study tests whether drinking smoothies made with Haskap berries can improve gut health and metabolism in people over eight weeks.

  Recruiting Montana State University · Bozeman, Montana · NCT06546020

• Collection of microbiome samples from healthy donors

  This study is collecting samples from healthy people to see how different types of germs in our bodies affect health and disease.

  Recruiting University Ghent · Ghent, East Flanders · NCT06466707

• Research on improving kindergarten yards for children's health

  This study is testing whether making kindergarten yards more natural and full of plants can improve the health and learning of children aged 1-5 by looking at things like allergies, asthma, and their overall well-being.

  Recruiting at 2 sites Natural Resources Institute Finland · Helsinki, Uusimaa and 1 other locations · NCT06390878

• Exploring how playing in sand affects atopic dermatitis in children

  This study is testing if playing in sand can help young children with eczema feel better by looking at their skin and immune system changes.

  Recruiting at 2 sites Natural Resources Institute Finland · Helsinki, Uusimaa and 1 other locations · NCT06390696

• Restoring gut bacteria in infants born by cesarean section

  This study is testing a new treatment to help restore healthy gut bacteria in infants born by cesarean section to see if it can improve their immune system development.

  Recruiting Phase 1 Copenhagen Studies on Asthma in Childhood · Gentofte Municipality, Copenhagen and 1 other locations · NCT06264219

• Using donor milk to improve gut health in cesarean-born infants

  This study is trying to see if giving cesarean-born babies donor human milk instead of formula can help their gut health and improve sleep and growth.

  Recruiting University of Calgary · Calgary, Alberta · NCT06177184

• Analyzing changes in oral microbiome during dental implant placement

  This study looks at how the bacteria in the mouth change when people with severe gum disease get dental implants and whether different implant materials affect these changes.

  Recruiting Case Western Reserve University · Cleveland, Ohio · NCT06149585

• Molecular culture for diagnosing sepsis in children

  This study is testing a faster way to diagnose sepsis in newborns and children by using a new blood test to see if it can identify infections more quickly than the usual method.

  Recruiting at 2 sites Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Amsterdam and 1 other locations · NCT06018792

• Using synbiotics to reduce the risk of preterm birth

  This study is testing if taking synbiotics can help women at high risk for preterm birth have healthier pregnancies by improving their vaginal microbiome.

  Recruiting at 9 sites Ziekenhuis Oost-Limburg · Edegem, Antwerpen and 8 other locations · NCT05966649

• Examining the genital microbiome of male partners of women with recurrent bacterial vaginosis

  This study is testing if the bacteria in the genital area of men can affect how often their female partners get bacterial vaginosis and whether cleaning with a certain solution can help reduce this risk.

  Recruiting Hadassah Medical Organization · Jerusalem · NCT05963711

• B. Infantis to Boost Immunity in Infants Exposed to HIV

  This study is testing if giving a probiotic to infants born to HIV-positive mothers can help boost their immunity and improve their gut health during the first few months of life.

  Recruiting University of Cape Town · Cape Town · NCT05923333

• Optimizing diet for patients with ulcerative colitis

  This study is testing if changing the diet by cutting out certain additives can help people with ulcerative colitis feel better and improve their gut health.

  Recruiting Region Skane · Malmö, Skåne County · NCT05743374

• Effects of mouthrinse on oral and gut bacteria and viruses

  This study is testing how two popular mouthwashes affect the bacteria and viruses in your mouth and gut over six months.

  Recruiting University of California, Irvine · Irvine, California · NCT05603650

• Assessing H. pylori infection rates and antibiotic resistance in Germany

  This study is trying to find out how common H. pylori infections are in Germany and if the bacteria are resistant to antibiotics, so doctors can better treat patients.

  Recruiting Technical University of Munich · Munich · NCT05561504

• Using broad-spectrum antibiotics to prevent infections in orthopedic surgery

  This study tests whether using a stronger type of antibiotics before orthopedic surgery can help prevent infections in patients who are at high risk.

  Recruiting Phase 3 Balgrist University Hospital · Zurich · NCT05502380

• Effects of Aronia Juice on Immune System and Depression

  This study is testing whether drinking aronia juice can boost the immune system and help people with depression feel better.

  Recruiting Medical University of Graz · Graz, Styria · NCT05432362

• Improving skin preparation for foot and ankle surgery

  This study tests if a new skin cleaning method before foot and ankle surgery can help lower the risk of infections compared to the usual cleaning method.

  Recruiting Phase 4 University of Missouri-Columbia · Columbia, Missouri · NCT05401292

• Exploring the microbiome in burn wounds using advanced sequencing techniques

  This study is trying to see how the germs in burn wounds affect healing and recovery in adults with serious burns.

  Recruiting The University of Texas Medical Branch, Galveston · Galveston, Texas · NCT05275335

• Investigating the microbiome's effect on pregnancy outcomes in women planning to conceive

  This study is trying to see how the bacteria in the body affect pregnancy outcomes for women who have given birth before and are planning to get pregnant again.

  Recruiting Karolinska Institutet · Stockholm, Huddinge and 1 other locations · NCT05127252

• Personalized dietary responses for better health

  This study is testing how different foods affect people's health based on their unique responses, and it's for individuals taking part in the ZOE testing program.

  Recruiting at 2 sites Zoe Global Limited · Needham, Massachusetts and 1 other locations · NCT04735835

• Tracking the development of healthy infant gut bacteria in Bern

  This study is looking at how healthy babies' gut bacteria grow and change during their first two years of life by following 250 pregnant moms and their kids for ten years.

  Recruiting Insel Gruppe AG, University Hospital Bern · Bern · NCT04447742

NIH-funded research (6)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Megaplasmids and gut microbes in babies and adults

  Scientists are studying unusually large plasmids found in the gut bacteria of babies and adults to understand how these big DNA pieces might affect health and antibiotic resistance.

  NIH research University of California Berkeley · Berkeley, United States · NIH-11450672

• Understanding Gut Bacteria in Premature Babies

  This project looks at how antibiotics given to premature babies right after birth affect the helpful bacteria in their gut.

  NIH research University of California Berkeley · Berkeley, United States · NIH-11118883

• How gut bacteria may steer feeding and behavior in a tiny worm

  This grant explores how gut bacteria influence the feeding choices and behavior of C. elegans, a simple worm often used to study biology.

  NIH research Yale University · New Haven, United States · NIH-11014675

• Understanding how microbes affect skin health in children with eczema

  This study is looking at how the tiny germs on the skin of kids with eczema might affect their skin condition, with the hope of finding new ways to help manage their symptoms.

  NIH research Cincinnati Childrens Hosp Med Ctr · Cincinnati, United States · NIH-11001841

• How early microbial exposure affects immune system development

  This study is looking at how the germs we encounter early in life can shape our immune system and overall health later on, using African Clawed Frogs to help us understand how this works, which might eventually help people with autoimmune diseases.

  NIH research University of Massachusetts Boston · Boston, United States · NIH-10730933

• How gut bacteria influence the feeding behavior of roundworms

  This study is looking at how the bacteria in the gut can influence the eating habits of tiny roundworms, which helps scientists learn more about how our own gut bacteria might affect our behavior and choices.

  NIH research Yale University · New Haven, United States · NIH-10686470

Related topics

Quick answers

How many Microbial Colonization clinical trials are recruiting right now?

24, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 14 countries. The most sites are in United States (7 trials), Belgium (3 trials), Sweden (2 trials), Switzerland (2 trials), Finland (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 2, Phase 3: 1, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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