Effects of mouthrinse on oral and gut bacteria and viruses

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This research investigates how two over-the-counter mouthwashes, Listerine and Lumineux Oral Essentials, affect the microbiome in the mouth and gastrointestinal tract. Participants will be randomly assigned to rinse with one of the mouthwashes or water twice daily for 180 days. The study includes five visits where oral plaque and fecal samples will be collected to analyze changes in microbial populations. The goal is to understand the impact of these mouthwashes on oral and gut health.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Eligible men and non-pregnant and non-lactating women of all races age 18-25.
* Volunteers must consent to participate in all scheduled exam visits and procedures.
* Volunteers must be available for follow up on the telephone.
* Healthy gums or gums that bleed when you brush them.

Exclusion Criteria:

* Volunteers unable or unwilling to sign the informed consent form.
* Less than 20 teeth (excluding third molars).
* Individuals who have taken antibiotics in the previous 3 months.
* Presence of any condition, abnormality, or situation at Baseline that in the opinion of the Principal Investigator may preclude the volunteer's ability to comply with study requirements, including completion of the study or the quality of the data.

Where it's running

• Beckman Laser Institute and Medical Clinic
  Irvine, California, United States Recruiting

Study contacts

• Principal investigator: Petra Wilder-Smith, DDS, PhD — University of Calfornia Irvine
• Study coordinator: Nicole Wakida, PhD
• Email: nwakida@uci.edu
• Phone: 949-824-4360

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.