NIH-funded research NIH-funded research

Adolescent and Youth HIV Prevention and Care Improvements in Uganda

Official title: Implementation Science to Understand and Design Stakeholder Informed Innovative Interventions to Improve Adolescent and Youth HIV Prevention and Care Continuums in Rural and Urban Uganda

Funded at Mu-Jhu Care · NIH-11478466 · Data updated 2026-11-12

A UG1 grant is testing ways to help Ugandan teens and young adults (ages 15-24) prevent HIV and stay healthy if they have HIV, using new long-acting PrEP and community care approaches.

More HIV Prevention research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMu-Jhu Care
NIH-funded
Lab location1 site (Kampala, Uganda)
Project startSeptember 8, 2023
Project endAugust 31, 2028
Funding year2026
Award (this year)$231,483
NIH project number3UG1HD113241-04S1
Project IDNIH-11478466 on NIH RePORTER

Who could benefit from this research

Could help

Ideal participants are adolescents and young adults aged 15-24 in Uganda at risk for HIV or living with HIV who can engage with community-based care delivery.

Less likely to help

Individuals outside the target age range or those not connected to the MOH-approved community service delivery models may see limited benefit.

What this research studies

This project focuses on adolescents and young adults in Uganda who are at risk for HIV or living with HIV. It will test how well evidence-based interventions work when delivering a new long-acting PrEP option (CAB-LA) and supportive care practices through youth-friendly community services. Researchers will combine stage-based assessments with tailored support to improve viral suppression and reduce barriers like stigma and access. The study uses implementation science methods to see how these interventions function in real-world settings and to identify best-fit delivery strategies. Outcomes will look at uptake, adherence, and care continuity across the HIV prevention and treatment cascade.

Why it matters

Potential benefit: If successful, the work could improve HIV prevention and treatment outcomes for Ugandan youth by increasing PrEP use, adherence, and viral suppression.

How similar studies have gone: Previous similar implementation studies suggest that tailored, youth-focused delivery models can improve PrEP uptake and adherence, but effectiveness in this specific setting is being tested.

Where this research is happening

  • Mu-Jhu Care
    Kampala, Uganda
    Active

Researchers

  • Principal investigator: Musoke, Philippa — Mu-Jhu Care
  • Study coordinator: Musoke, Philippa

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.