NIH-funded research R01 grant

Understanding how poverty and environment influence heart disease and health in adults

Official title: Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders

Funded at Washington University · NIH-11535757 · Data updated 2026-11-12

A study follows adults in a long-term cohort to understand how poverty, stress, diet, and pollution affect heart and blood conditions.

More Implementation Science research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWashington University
NIH-funded
Lab location1 site (Saint Louis, United States)
Project startSeptember 10, 2026
Project endJune 30, 2028
Funding year2026
Award (this year)$744,353
NIH project number7R01HL143788-09
Project IDNIH-11535757 on NIH RePORTER

Who could benefit from this research

Could help

Adults with a history of poverty-related risk factors and enrolled in or eligible for the Haiti CVD Cohort or similar poverty-affected populations.

Less likely to help

Individuals without access to long-term follow-up or without exposure to poverty-related risk factors may see limited direct benefit.

What this research studies

This project builds on a well-characterized group of adults from the Haiti CVD Cohort and tracks them over several years to identify how poverty-related factors contribute to cardiovascular risks and events. It uses longitudinal data to connect living conditions, diet (like salt intake), stress, and environmental exposures to health outcomes. The findings aim to guide community interventions and inform prevention strategies that could reduce heart disease risk in vulnerable populations. Participants would contribute health information and potentially biospecimens as part of ongoing follow-up.

Why it matters

Potential benefit: If successful, the study could lead to targeted prevention and intervention strategies to reduce heart disease risk among people living in poverty.

How similar studies have gone: Previous work in this cohort has shown links between poverty-related factors and cardiovascular risk, with ongoing follow-up planned to establish causality.

Where this research is happening

  • Washington University
    Saint Louis, United States
    Active

Researchers

  • Principal investigator: Mcnairy, Margaret Leighton — Washington University
  • Study coordinator: Mcnairy, Margaret Leighton

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About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.