NIH-funded research NIH-funded research

Innovative HIV Prevention and Care Interventions for Adolescents and Young Adults in Uganda

Official title: Implementation Science to Understand and Design Stakeholder Informed Innovative Interventions to Improve Adolescent and Youth HIV Prevention and Care Continuums in Rural and Urban Uganda

Funded at Mu-Jhu Care · NIH-11644068 · Data updated 2026-11-12

A Ugandan research team is testing practical, youth-focused strategies to help 15-24 year-olds using HIV prevention or treatment services stay healthy and engaged in care.

More HIV Prevention research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMu-Jhu Care
NIH-funded
Lab location1 site (Kampala, Uganda)
Project startSeptember 8, 2023
Project endAugust 31, 2028
Funding year2026
Award (this year)$216,390
NIH project number3UG1HD113241-04S3
Project IDNIH-11644068 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are adolescents and young adults aged 15-24 in Uganda who are at high risk for HIV or are living with HIV and need support to stay adherent and virally suppressed.

Less likely to help

Young people outside the 15-24 age range or those not engaged in HIV prevention or care activities may not benefit from these specific interventions.

What this research studies

This project works with adolescents and young adults in Uganda to improve how HIV prevention and care services are delivered and used. It will test community-based models and long-acting cabotegravir (CAB-LA) delivery to make PrEP and viral suppression more accessible and acceptable for youth. Using real-world settings, the study combines screening for HIV risk, youth-friendly trials, and MOH-approved service delivery approaches to support sustained engagement in prevention and care. Researchers will assess how well these interventions work in reducing barriers and improving outcomes along the HIV care cascade.

Why it matters

Potential benefit: If successful, it could make HIV prevention and treatment more effective for Ugandan youth, reducing new infections and helping more HIV-positive young people achieve viral suppression.

How similar studies have gone: Previous work suggests tailored, youth-focused delivery models can improve uptake and adherence, with further evidence needed for long-acting PrEP in real-world settings.

Where this research is happening

  • Mu-Jhu Care
    Kampala, Uganda
    Active

Researchers

  • Principal investigator: Musoke, Philippa — Mu-Jhu Care
  • Study coordinator: Musoke, Philippa

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.