NIH-funded research NIH-funded research

Improving HIV Prevention and Care for Ugandan Adolescents and Young Adults

Official title: Implementation Science to Understand and Design Stakeholder Informed Innovative Interventions to Improve Adolescent and Youth HIV Prevention and Care Continuums in Rural and Urban Uganda

Funded at Mu-Jhu Care · NIH-11478467 · Data updated 2026-11-12

A Uganda-based research effort aims to boost HIV prevention and care outcomes for 15-24 year-olds by testing practical, community-based strategies to increase PrEP use and viral suppression.

More HIV Prevention research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMu-Jhu Care
NIH-funded
Lab location1 site (Kampala, Uganda)
Project startSeptember 8, 2023
Project endAugust 31, 2028
Funding year2026
Award (this year)$195,675
NIH project number3UG1HD113241-04S2
Project IDNIH-11478467 on NIH RePORTER

Who could benefit from this research

Could help

Ideal participants are adolescents and young adults aged 15-24 in Uganda, including HIV-negative individuals at risk and people living with HIV needing care optimization.

Less likely to help

Some individuals may not see direct benefit if CAB-LA is not suitable or if access barriers persist.

What this research studies

This project focuses on adolescents and young adults in Uganda who are at high risk for HIV or living with HIV. It will test and implement evidence-based approaches, including long-acting PrEP (CAB-LA) delivery through community models and youth-focused support, to improve uptake and adherence. Researchers will use new screening methods and collaborative teams experienced in youth clinical trials and implementation science to measure how well these strategies work in real-world settings. The study uses a hybrid design to simultaneously assess how well the interventions work and how they can be implemented in MOH-supported programs.

Why it matters

Potential benefit: If successful, the work could lead to higher PrEP use and better viral suppression among Ugandan youth, reducing new infections and improving health outcomes.

How similar studies have gone: Previous implementation research in similar settings has shown that community-based delivery and youth-focused support can improve PrEP uptake and adherence.

Where this research is happening

  • Mu-Jhu Care
    Kampala, Uganda
    Active

Researchers

  • Principal investigator: Musoke, Philippa — Mu-Jhu Care
  • Study coordinator: Musoke, Philippa

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.