NIH-funded research NIH-funded research

Making HIV prevention and care easier for Ugandan youth

Official title: Implementation Science to Understand and Design Stakeholder Informed Innovative Interventions to Improve Adolescent and Youth HIV Prevention and Care Continuums in Rural and Urban Uganda

Funded at Mu-Jhu Care · NIH-11644400 · Data updated 2026-11-12

A Ugandan study is testing ways to help adolescents and young adults (15–24) prevent HIV and stay healthy, using long-acting PrEP and youth-friendly services.

More HIV Prevention research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMu-Jhu Care
NIH-funded
Lab location1 site (Kampala, Uganda)
Project startSeptember 8, 2023
Project endAugust 31, 2028
Funding year2026
Award (this year)$231,482
NIH project number3UG1HD113241-04S4
Project IDNIH-11644400 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are adolescents and young adults aged 15–24 in Uganda who are at risk for HIV or living with HIV and are enrolled in or eligible for the CAB-LA delivery models.

Less likely to help

Youth outside the target age range or in settings without access to the MOH-approved service delivery models may experience limited benefit.

What this research studies

This project focuses on AYA in Uganda who are at high risk for HIV or living with HIV. It tests evidence-based interventions to improve PrEP uptake and viral suppression, using community-based delivery models for long-acting CAB-LA and youth-centered care. The study will screen for HIV risk with new methods, apply MOH-approved differentiated service delivery, and use implementation science to see how well these approaches work in real-world settings. Researchers will combine clinical data with implementation outcomes to understand what helps or hinders success in youth care pathways.

Why it matters

Potential benefit: If successful, the interventions could increase PrEP use and viral suppression among Ugandan youth, reducing new infections and improving health outcomes.

How similar studies have gone: Previous studies in similar settings suggest that youth-focused, differentiated care can improve adherence and prevention outcomes, but this study tests a multi-component, implementation-focused approach in Uganda.

Where this research is happening

  • Mu-Jhu Care
    Kampala, Uganda
    Active

Researchers

  • Principal investigator: Musoke, Philippa — Mu-Jhu Care
  • Study coordinator: Musoke, Philippa

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.