NIH-funded research R01 grant

Making HIV care work better with high blood pressure prevention

Official title: From Evidence to Scale: Implementation Science and Simulation Modeling to Transform HIV-Hypertension Care Integration

Funded at University of California, San Francisco · NIH-11420765 · Data updated 2026-11-12

A program will test if integrating HIV care with blood pressure prevention and management can improve health outcomes and be cost-effective in African health systems.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco
NIH-funded
Lab location1 site (San Francisco, United States)
Project startJune 10, 2026
Project endFebruary 28, 2029
Funding year2026
Award (this year)$2,340,260
NIH project number1R01HL187196-01
Project IDNIH-11420765 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates include people in settings with HIV and hypertension care needs, health systems looking to integrate services, and decision-makers planning scalable implementation.

Less likely to help

Patients in very rural or severely resource-limited settings without access to primary care may face implementation barriers.

What this research studies

This project will expand an HIV modeling tool to include hypertension and heart disease outcomes, and will use data from clinical trials in six African countries to test scalable ways to integrate HIV and blood pressure care. Researchers will simulate different implementation strategies to see which ones deliver the best health benefits within real health system constraints. The work aims to show how to improve primary care for people with HIV and those without HIV while keeping services affordable and sustainable. Results could guide policymakers and funders on the best paths to scale integration of HIV and hypertension care.

Why it matters

Potential benefit: If successful, the project could inform scalable, cost-effective ways to reduce heart disease risk for people living with HIV and the broader population.

How similar studies have gone: Previous HIV modeling and cluster trials have shown potential benefits; this project builds on that with a focus on hypertension integration.

Where this research is happening

  • University of California, San Francisco
    San Francisco, United States
    Active

Researchers

  • Principal investigator: Hickey, Matthew — University of California, San Francisco
  • Study coordinator: Hickey, Matthew

Related research

Other NIH-funded projects on the same topics.

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  • Improving depression treatment for African American adults with high blood pressure

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    NIH research Northwestern University at Chicago · Chicago, United States · NIH-11011365

  • Improving care for patients with resistant hypertension using electronic health records

    This study is looking to help people with stubborn high blood pressure by using technology to better understand who really has resistant hypertension and who might just need a different approach, so doctors can give the best care possible.

    NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-10896423

  • Improving colorectal cancer screening and follow-up care.

    This study is working to help more people get screened for colorectal cancer and receive the follow-up care they need, especially those who haven't been screened much before, so that everyone can have better access to important health checks and improve their overall health.

    NIH research Research Triangle Institute · Research Triangle Park, United States · NIH-9627071

  • HEARTS hypertension and diabetes care in Guatemala

    This grant tests how well the HEARTS primary care model works in Guatemala to improve blood pressure and blood sugar control for patients.

    NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11645315

  • Making HIV prevention and care easier for Ugandan youth

    A Ugandan study is testing ways to help adolescents and young adults (15–24) prevent HIV and stay healthy, using long-acting PrEP and youth-friendly services.

    NIH research Mu-Jhu Care · Kampala, Uganda · NIH-11644400

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.