HIV care options tailored to patients' needs
Official title: Differentiated HIV Care Models: An Implementation Science Study
Funded at Duke University · NIH-11474700 · Data updated 2026-11-12
This project compares different ways of delivering HIV care to help adults on treatment or using PrEP stay on treatment, keep the virus suppressed, or avoid infection.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project start | October 1, 2023 |
| Project end | February 28, 2027 |
| Funding year | 2026 |
| Award (this year) | $245,778 |
| NIH project number | 3R01MH130277-06S1 |
| Project ID | NIH-11474700 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults receiving HIV treatment (ART) or taking PrEP at participating clinics in South Africa would be the ideal candidates for this work.
✕Less likely to help
Children, people not attending the participating clinics, or those outside the study areas in South Africa are unlikely to be included or benefit directly from this project.
What this research studies
You would be followed at clinics in South Africa where some offer 'differentiated' care (for example, community pick-up, integrated primary care, or stigma-reduction practices) while others use standard clinic services. Researchers will watch clinic processes, interview staff, and do repeated in-depth interviews with clients to learn about what helps or gets in the way. They will also follow groups of clients over time and use medical records and viral load/PrEP data to compare outcomes between the different clinic approaches. The team will look at both health outcomes and the costs and acceptability of adding primary care or stigma-reduction into HIV services.
Why it matters
Potential benefit: If successful, this work could make it easier for people to stay on HIV treatment or PrEP and increase viral suppression and prevention in real-world clinics.
How similar studies have gone: Other demonstration projects of differentiated service delivery have shown promise for improving retention and convenience, but rigorous multi-site comparisons of clinical outcomes and costs remain limited.
Where this research is happening
-
Duke University
Durham, United States Active
Researchers
- Principal investigator: Poteat, Tonia C — Duke University
- Study coordinator: Poteat, Tonia C
Related research
Other NIH-funded projects on the same topics.
-
Improving colorectal cancer screening and follow-up care.
This study is working to help more people get screened for colorectal cancer and receive the follow-up care they need, especially those who haven't been screened much before, so that everyone can have better access to important health checks and improve their overall health.
-
Making HIV prevention and care easier for Ugandan youth
A Ugandan study is testing ways to help adolescents and young adults (15–24) prevent HIV and stay healthy, using long-acting PrEP and youth-friendly services.
-
Innovative HIV Prevention and Care Interventions for Adolescents and Young Adults in Uganda
A Ugandan research team is testing practical, youth-focused strategies to help 15-24 year-olds using HIV prevention or treatment services stay healthy and engaged in care.
-
How Poverty and the Environment Affect Heart Disease in Haiti and Beyond
This grant studies how poverty-related factors like food insecurity, stress, and pollution contribute to heart disease and aims to follow a large group of adults to better understand and prevent the disease.
-
Resilient HIV Implementation for LGBTQ Youth in Africa and Beyond
A program to help young people ages 15–24 who are at risk for or living with HIV, especially sexual and gender minority youths, access better HIV prevention and care through real-world health practice improvements.
-
Regional hub to speed up ending HIV with practical science
A regional collaboration will translate proven HIV interventions into real-world practice to reduce new infections across priority areas.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.