Condition

ICU Acquired Weakness clinical trials and research

• 11Clinical trials
• 2NIH research projects
• 7Countries

Newest ICU Acquired Weakness clinical trials

All recruiting trials (11)

• Can a handheld nerve monitor detect early ICU weakness in healthy people and ICU patients

  This study tests whether a non-invasive nerve monitor (TetraGraph) can spot early signs of ICU-acquired weakness by comparing its readings with standard nerve tests in healthy volunteers and ICU patients.

  Recruiting Endeavor Health · Evanston, Illinois · NCT07699562

• MyokinE100 System: Closed Loop Electrical Muscle Stimulation to Help ICU Patients Maintain Muscle Strength

  This trial tests whether adding daily 60-minute thigh electrical muscle stimulation to standard ICU care is safe and easy for adults with sepsis or critical illness to see if it slows ICU-acquired muscle weakness.

  Recruiting at 3 sites Health Discovery Labs · Rochester, Minnesota and 2 other locations · NCT07362862

• ICU‑Recover Box 2.0: smart home monitoring for people after an ICU stay.

  This pilot tests whether a home ICU‑Recover Box with smart sensors can help people recovering from an ICU stay detect problems early and support recovery during the year after discharge.

  Recruiting Leiden University Medical Center · Leiden, South Holland · NCT07162948

• Sitting ventilated ICU patients in an armchair to improve recovery.

  This test will try sitting adults on mechanical ventilation in an armchair to see if it helps their breathing, strength, and recovery after an ICU stay.

  Recruiting at 8 sites Centre Hospitalier Régional d'Orléans · Orléans, Centre-Val de Loire and 10 other locations · NCT06973746

• Rehabilitation of hand and arm function using virtual reality

  This study is testing if a fun virtual reality game can help improve hand and arm strength in ICU patients who have been in the hospital for a while, compared to regular rehab methods.

  Recruiting Frisius Medisch Centrum · Leeuwarden, Provincie Friesland · NCT06373341

• Evaluating muscle weakness in ICU survivors through exercise testing

  This study is trying to see how problems with blood flow after being in the ICU affect the strength and exercise ability of patients who survived serious illnesses like sepsis and shock.

  Recruiting at 2 sites University of Manitoba · Winnipeg, Manitoba and 1 other locations · NCT06193980

• Improving ICU care through behavioral strategies

  This study is testing two strategies to help ICU staff use better practices for caring for critically ill adults, especially those facing health challenges, to see if it can improve patient recovery and reduce complications.

  Recruiting at 3 sites University of Nebraska · Iowa City, Iowa and 2 other locations · NCT06184945

• Combining muscle activation and high-protein nutrition to improve muscle health in ICU patients

  This study is testing if giving high-protein nutrition along with muscle activation exercises can help critically ill patients in the ICU keep their muscles strong and recover better.

  Recruiting at 2 sites Technical University of Munich · Vienna, State of Vienna and 3 other locations · NCT05919940

• Optimized nutritional therapy with early physiotherapy for long-stay ICU patients

  This program tests whether better-tailored nutrition combined with early physiotherapy helps adults on ventilators who are expected to stay in the ICU seven days or more leave the hospital with stronger muscles.

  Recruiting University Hospital, Geneva · Geneva, Canton of Geneva · NCT05865314

• Understanding muscle recovery in ICU survivors

  This study looks at how well muscle function and physical abilities recover in people who have survived serious illnesses and spent time in the ICU.

  Recruiting University of Kentucky · Birmingham, Alabama and 2 other locations · NCT05537298

• Mobile health program for rehabilitation after COVID-19

  This study is testing a mobile health program that uses high intensity exercise to help 120 patients recover better after being seriously ill with COVID-19.

  Recruiting at 5 sites Duke University · Birmingham, Alabama and 4 other locations · NCT05218083

NIH-funded research (2)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Safer automated muscle stimulation to prevent ICU-acquired weakness

  This project builds an automated muscle-stimulation device to help people in the ICU keep muscle strength and make it easier to come off mechanical ventilation.

  NIH research Health Discovery Labs LLC · Austin, United States · NIH-11182586

• Developing a system to use electrical stimulation for preventing muscle weakness in ICU patients

  This study is testing a new device that uses gentle electrical pulses to help keep your muscles strong while you're in the ICU, so you can recover better and avoid weakness from being in bed for a long time.

  NIH research Health Discovery Labs LLC · Austin, United States · NIH-10920531

Related topics

Quick answers

How many ICU Acquired Weakness clinical trials are recruiting right now?

11, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in United States (5 trials), Netherlands (2 trials), Canada (1 trial), Austria (1 trial), Germany (1 trial). Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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