Developing a system to use electrical stimulation for preventing muscle weakness in ICU patients

Closed Loop Electrical Muscle Stimulation System (CL-EMS) with improved safety for ICU environment to mitigate ICU Acquired Weakness

NIH-funded research Health Discovery Labs LLC · NIH-10920531

This study is testing a new device that uses gentle electrical pulses to help keep your muscles strong while you're in the ICU, so you can recover better and avoid weakness from being in bed for a long time.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionHealth Discovery Labs LLC NIH-funded
Lab location1 site (Austin, United States)
Project IDNIH-10920531 on NIH RePORTER

What this research studies

This research aims to create a closed loop electrical muscle stimulation (CL-EMS) system designed specifically for use in intensive care units (ICUs) to help prevent ICU acquired weakness (ICUAW). ICUAW can develop quickly due to factors like prolonged bed rest and the effects of medications, leading to significant muscle weakness and complications. The CL-EMS system will use electrical pulses to stimulate muscles passively, allowing for early intervention even in patients who are critically ill and unable to participate in traditional rehabilitation. This approach seeks to improve patient outcomes by mitigating the effects of muscle atrophy during their ICU stay.

Who could benefit from this research

Good fit: Ideal candidates for this research are critically ill patients admitted to the ICU who are at risk of developing ICU acquired weakness.

Not a fit: Patients who are not critically ill or those who do not require ICU care may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce muscle weakness and improve recovery times for critically ill patients in the ICU.

How similar studies have performed: Previous studies have shown promise in using electrical muscle stimulation for rehabilitation, but this specific application in the ICU setting is novel.

Where this research is happening

Austin, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.