AI-simplified versus original patient education materials for parents of children with osteogenesis imperfecta

AI-Simplified Patient Educational Materials: Investigating the Potential for Improved Patient Comprehension and Health Literacy

Not applicable Interventional Hospital for Special Surgery, New York · NCT07505719

This tests whether AI-simplified educational materials help parents of children with osteogenesis imperfecta understand the condition better than the original materials.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment80 (estimated)
Ages18 Years and up
SexAll
SponsorHospital for Special Surgery, New York Academic / other
Locations1 site (New York, New York)
Trial IDNCT07505719 on ClinicalTrials.gov

What this trial studies

Poor health literacy is linked to worse health outcomes, and many patient education materials are written above recommended reading levels. In this interventional study, parents or guardians of pediatric patients at Hospital for Special Surgery will receive either the original patient educational material or an AI-simplified version and then complete measures of comprehension and related questionnaires. The trial excludes non-English speakers, healthcare professionals, and those with prior detailed knowledge of osteogenesis imperfecta. Primary outcomes focus on patient comprehension and perceived clarity, with secondary measures that may include readability metrics and satisfaction.

Who should consider this trial

Good fit: Parents or guardians of pediatric patients receiving care at Hospital for Special Surgery who speak English, are not healthcare professionals, and do not already have detailed knowledge about osteogenesis imperfecta.

Not a fit: Non-English-speaking caregivers, people whose primary job is in healthcare, or those already familiar with osteogenesis imperfecta are unlikely to gain additional benefit from the simplified materials.

Why it matters

Potential benefit: If successful, this approach could make medical information easier for parents to understand and support better decision-making and care for their children.

How similar studies have performed: Previous work shows large language models can lower the reading grade level of patient materials, but few studies have demonstrated that AI-simplified text improves actual patient comprehension.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Parents or guardians of pediatric patients receiving treatment at Hospital for Special Surgery

Exclusion Criteria:

* Non-English Speaking
* primary occupation is in healthcare
* participants with prior knowledge on the condition pertaining to the material (osteogenesis imperfecta)

Where this trial is running

New York, New York

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Artificial IntelligenceHealth LiteracyPatient ComprehensionPatient Educational Material
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.