Agentic LLM for Shared Decision Making in Health Care

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers will compare an agentic LLM chatbot designed to support SDM with a standard LLM chatbot and a traditional information brochure. The study focuses on adults aged 40–70 in the US or UK who are native English speakers and Prolific users, evaluating whether the agentic system improves understanding and participation in decision making. It uses a state-machine approach to maintain context, reduce over-enthusiastic responses, and better tailor information to reading level. Outcomes will assess accuracy, user comprehension, and engagement in multi-turn conversations. Overall, the trial explores whether this architecture can promote more informed decisions in a digital health setting.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Biological sex: Female.
* Age: 40 to 70 years old.
* Country of residence: United States (US) or United Kingdom (UK).
* Language: Native English speaker (English as first language).
* Registered and verified user on the academic research platform Prolific.
* Able to read, understand, and provide informed consent digitally.

Exclusion Criteria:

* Individuals who do not meet the automated pre-screening criteria on the Prolific platform.
* Inability to use or access a computer, smartphone, or internet browser required to complete the digital study.

Note: Quotas will be enforced during recruitment to ensure a 50/50 stratified split between participants with and without university entrance qualifications to guarantee variance in educational backgrounds. Once a quota is filled, further participants matching that educational profile will be excluded.

* Addendum: Women with BC symptoms

Where it's running

• Brandenburg Medical School Theodor Fontane
  Neuruppin, Germany Recruiting

Study contacts

• Principal investigator: Felix G Rebitschek, PhD — Harding Center for Risk Literacy
• Study coordinator: Felix G Rebitschek, PhD
• Email: felix.rebitschek@fgw-brandenburg.de
• Phone: +493319772162

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.