NIH-funded research NIH-funded research

Health literacy and thinking skills in older adults and caregivers

Official title: LitCog V: Health Literacy and Cognitive Function Among Older Adults

Funded at Northwestern University · NIH-10979423 · Data updated 2026-11-12

This long-term project follows older adults and their caregivers to track how thinking skills and health literacy change and affect managing health.

More Cognitive Function research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionNorthwestern University
NIH-funded
Lab location1 site (Chicago, United States)
Project startSeptember 15, 2007
Project endAugust 31, 2029
Funding year2025
Award (this year)$3,782,845
NIH project number2RF1AG030611-18
Project IDNIH-10979423 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are older adults (especially those 55 and up) with one or more chronic conditions and their informal caregivers, typically living in or near the Chicago area.

Less likely to help

People under 55, those without chronic health needs, or anyone seeking an experimental treatment are unlikely to get direct medical benefit from this observational project.

What this research studies

Since 2007, researchers have followed a group of adults (initially ages 55–74) and their caregivers with detailed interviews every three years to measure thinking skills, health literacy, medication use, and daily functioning. Participants complete cognitive and health interviews, questionnaires about self-care and social factors, and some medical record checks. The team analyzes which psychological, social, and behavioral factors speed or slow declines and how those declines affect treatment adherence and independence. Findings are used to shape ways to support older adults and caregivers with education, tools, or care changes.

Why it matters

Potential benefit: If successful, this work could point to practical ways to help older adults and caregivers maintain safer self-care and independence.

How similar studies have gone: Previous phases of the LitCog cohort have already shown links between declining cognition, lower health literacy, and worse self-care, so this work builds on established findings.

Where this research is happening

  • Northwestern University
    Chicago, United States
    Active

Researchers

  • Principal investigator: Wolf, Michael S — Northwestern University
  • Study coordinator: Wolf, Michael S

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.