Condition

Irritable Bowel Syndrome (IBS) clinical trials and research

• 19Clinical trials
• 3NIH research projects
• 1New in 30 days
• 14Countries

Newest Irritable Bowel Syndrome (IBS) clinical trials

All recruiting trials (19)

• Vitamin D Supplementation in Children with Irritable Bowel Syndrome

  This study tests whether giving vitamin D to children with IBS and low vitamin D levels can improve their IBS symptoms compared with a placebo.

  Recruiting Aziz Bhatti Shaheed Teaching Hospital · Gujrat, Punjab Province · NCT07914478

• IBS-oriented Crohn's Disease Exclusion Diet versus Low FODMAP Diet for IBS

  This study tests whether an IBS-adapted Crohn's Disease Exclusion Diet (CDED) can better help adults with IBS-D or IBS-M than the low FODMAP diet.

  Recruiting Ariel University · Ramat Gan, Tel Aviv · NCT07707635

• How certain FODMAPs affect IBS pain in adults

  This study tests whether adding back specific FODMAP types after a low-FODMAP diet can reveal which ones drive abdominal pain in adults with IBS.

  Recruiting Queen's University · Kingston, Ontario · NCT07688044

• Gut–brain gut study in IBS with anxiety and depression

  This study will compare people with IBS and mood symptoms to healthy volunteers to see if gut bacteria relate to brain function using questionnaires, stool and blood samples, and a brain MRI.

  Recruiting Tang-Du Hospital · Xi'an, Shaanxi · NCT07646834

• Pregabalin for irritable bowel syndrome in adults

  A clinician-led study will test whether pregabalin helps adults with irritable bowel syndrome who meet specific symptom criteria.

  Recruiting Beijing Tiantan Hospital · Beijing, Beijing Municipality · NCT07635394

• Probiotic combination for irritable bowel syndrome

  This trial will test whether a daily probiotic capsule lowers symptom severity and affects gut transit time in adults with IBS.

  Recruiting Sahlgrenska University Hospital · Gothenburg · NCT07584278

• Lyophilized donor gut bacteria capsules for treating irritable bowel syndrome

  This trial will test whether taking oral freeze-dried fecal microbiota capsules can help adults 18–65 with IBS that hasn't responded to usual treatments.

  Recruiting Phase 1/2 University of Rijeka · Rijeka · NCT07481422

• Diet and wearable monitoring of gut movement in children with IBS

  This project will use a wearable patch, diet recall, and stool and urine samples to see if certain foods, gut movement patterns, or microbes are linked to symptoms in children ages 8–18 with IBS.

  Recruiting Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT07283341

• Long-term effectiveness and safety of fecal microbiota transplantation

  This project will follow about 4,000 people who have had fecal microbiota transplantation to see if it helps keep them in remission and is safe over 3 months, 1 year, and 5 years for conditions like recurrent C. difficile, IBD, IBS, and chronic constipation.

  Recruiting Shanghai 10th People's Hospital · Shanghai, Shanghai Municipality · NCT07261826

• Guided imagery therapy app for kids with functional abdominal pain

  This study tests a guided imagery therapy app to see if it helps school-age children with functional abdominal pain disorders.

  Recruiting at 2 sites Baylor College of Medicine · Austin, Texas and 1 other locations · NCT07222943

• Osteopathic care plus a flexible low‑FODMAP diet for people with fibromyalgia and IBS

  This project will see if adding osteopathic care to a flexible low‑FODMAP diet helps adults with fibromyalgia who also have moderate-to-severe IBS.

  Recruiting Universitair Ziekenhuis Brussel · Brussels, Brussels Capital · NCT07176078

• Probiotic Mix for Kids with Irritable Bowel Syndrome

  This study tests whether a specific probiotic blend can help children and teens with IBS feel better and have more regular bowel habits.

  Recruiting at 2 sites University of Bari · Bari, Bari and 2 other locations · NCT07125625

• How different FODMAP diets affect people with IBS and functional dyspepsia

  This test will try low FODMAP, gentle FODMAP, and standard dietary advice in adults with IBS or functional dyspepsia to see how they change symptoms, gut bacteria, gut barrier function, and quality of life.

  Recruiting Universiti Kebangsaan Malaysia Medical Centre · Kuala Lumpur, Kuala Lumpur · NCT07000227

• Comparing a low-FODMAP diet program versus exposure-based cognitive behavioral therapy for people with IBS

  This project will test whether an online low-FODMAP diet program or an online exposure-based cognitive behavioral therapy better reduces IBS symptoms in adults.

  Recruiting University of Melbourne · Melbourne, Victoria · NCT06940596

• Identifying genetic factors that predict dietary intervention success in IBS

  This study is trying to find out if certain genes can help predict how well people with Irritable Bowel Syndrome will respond to a special diet that combines low FODMAP and Mediterranean foods.

  Recruiting Attikon Hospital · Athens · NCT06912828

• Observing naturopathic treatments for irritable bowel syndrome

  This study looks at how naturopathic treatments can help adults with irritable bowel syndrome feel better by tracking their symptoms and quality of life before and after treatment.

  Recruiting National University of Natural Medicine · Portland, Oregon · NCT06721624

• Gelsectan® for treating diarrhea-predominant irritable bowel syndrome

  This study is testing if Gelsectan® can help people with diarrhea-predominant irritable bowel syndrome feel better.

  Recruiting at 12 sites Devintec Sagl · Leuven and 11 other locations · NCT06681012

• Diet challenge to study irritable bowel syndrome and gut microbiota

  This study is testing how a specific diet affects gut bacteria and bowel symptoms in people with irritable bowel syndrome to see if it helps them feel better.

  Recruiting University of California, Los Angeles · Los Angeles, California · NCT06668922

• Registry for gastrointestinal motility disorders at Indiana University

  This study is creating a detailed list of patients with gastrointestinal motility disorders to help doctors better understand and treat these conditions.

  Recruiting Indiana University · Indianapolis, Indiana · NCT04506593

NIH-funded research (3)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• IBS after COVID-19: how SARS-CoV-2 infection may lead to irritable bowel syndrome

  This project explores whether people who had SARS-CoV-2 infection may develop IBS and what factors raise that risk.

  NIH research University of Arizona · Tucson, United States · NIH-11375083

• Using a device at home to stimulate a nerve in the ear to help manage pain in young adults with IBS

  This study is looking at whether a gentle ear stimulation technique done at home can help young adults with irritable bowel syndrome (IBS) feel better by easing their pain and symptoms.

  NIH research Yale University · New Haven, United States · NIH-11122461

• Identifying biomarkers for diarrhea-predominant irritable bowel syndrome using stool samples

  This study is looking to make it easier to diagnose diarrhea-predominant irritable bowel syndrome (IBS-D) by checking stool samples for certain markers, so if you have IBS-D, researchers want to find a simple and non-invasive way to help identify your condition better.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11013340

Related topics

Quick answers

How many Irritable Bowel Syndrome (IBS) clinical trials are recruiting right now?

19, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 14 countries. The most sites are in United States (5 trials), China (3 trials), Italy (2 trials), Belgium (2 trials), Greece (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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