Prokinetics and Body Surface Gastric Mapping in Dyspeptic Patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study uses the Gastric Alimetry body surface mapping device to record gastric myoelectrical activity before and after starting a prokinetic or symptom-modulating therapy in adults with gastroparesis or functional dyspepsia. Researchers aim to identify baseline mapping features that may forecast which patients will respond to treatment. The study collects two non-invasive recordings and correlates them with changes in symptoms to guide personalized therapy choices. It is conducted at sites in Auckland, Philadelphia, and Sydney with collaboration across multiple institutions. No experimental therapies are introduced beyond standard clinical care plus the BSGM assessment.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients 18 years of age and older
* Diagnosis of gastroparesis and/or functional dyspepsia
* Being prescribed a prokinetic agent or symptom modulator for their clinical care
* Able to undergo BSGM recording both before and during treatment
* Able to give informed consent for undergoing a baseline BSGM recording and an additional recording while on treatment

Exclusion Criteria:

* Under 18 years of age
* Prior surgery on esophagus, stomach (appendectomy and cholecystectomy are allowed)
* History of skin allergies or a history of extreme sensitivity to cosmetics or lotions
* Pregnant women
* No vulnerable groups such as prisoners, individuals with known cognitive impairment, or institutionalized individuals be involved

Where it's running

• Western Sydney University
  Sydney, New South Wales, Australia Recruiting
• Te Whatu Ora Waitemata
  Auckland, Auckland, New Zealand Recruiting
• Temple University
  Philadelphia, Pennsylvania, United States Not yet recruiting

Study contacts

• Principal investigator: Henry Parkman, MD — Temple University
• Study coordinator: Genevieve M Johnston, PhD
• Email: gen.johnston@auckland.ac.nz
• Phone: +64 9 373 7599

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Assessing gastric functions in patients with diabetes

  This study looks at how diabetes affects stomach function in people with Type 1 and Type 2 diabetes to see if there are any problems and how these issues relate to their overall health.

  Recruiting at 5 sites Institute for Clinical and Experimental Medicine · Ostrava and 4 other locations · NCT06068114

• Low-FODMAP Diet vs Standard Dietary Advice for Functional Dyspepsia

  This study tests whether a low-FODMAP diet helps adults with functional dyspepsia compared with standard dietary advice.

  Recruiting King Chulalongkorn Memorial Hospital · Bangkok, Pathumwan · NCT07925073

• Gastric-focused ultrasound to see if it changes stomach activity and symptoms

  This study tests whether noninvasive stomach-focused ultrasound can alter post-meal stomach electrical activity and symptoms in adults with gastroparesis or delayed gastric emptying, using a sham control in a crossover design.

  Recruiting University of Texas at Austin · Austin, Texas · NCT07851727

• Pain Reprocessing Therapy for Functional Dyspepsia

  A small pilot test to see if a psychological therapy that uses exposure techniques can lessen digestive symptoms and help daily functioning in people with functional dyspepsia.

  Recruiting Mayo Clinic · Rochester, Minnesota · NCT07838324

• Gastric emptying and feeding tolerance in ICU patients by vasopressor dose

  This study tests whether vasopressor dose affects how well stomach contents empty during tube feeding in critically ill patients.

  Recruiting Başakşehir Çam & Sakura City Hospital · Istanbul · NCT07802379

• Identifying Signatures of Gut Interoception in Functional Dyspepsia and Anorexia Nervosa

  This study tests how the gut-brain connection works in people with functional dyspepsia or anorexia nervosa using brain imaging.

  Recruiting Massachusetts General Hospital · Boston, Massachusetts · NCT07772167

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.