Electroacupuncture to relieve functional dyspepsia symptoms

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults diagnosed with functional dyspepsia by Rome IV criteria will be assigned to receive 5 Hz electroacupuncture, 100 Hz electroacupuncture, or sham electroacupuncture and followed for symptom changes. Treatments are delivered at specific acupoints according to the study protocol and responses will be compared overall and by FD subtype (postprandial distress syndrome and epigastric pain syndrome). Key eligibility requirements include normal endoscopy within the past year and exclusion of patients with H. pylori infection, recent conflicting medication use, or serious comorbidities. The trial aims to determine whether either frequency produces greater symptom relief than sham and whether frequency effects differ between FD subtypes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosed with functional dyspepsia based on Rome IV diagnostic criteria.
* Aged 18 to 80 years, inclusive, with no gender restrictions.
* Normal endoscopy results within the past year, showing no structural explanation for symptoms.
* No acupuncture treatment in the last month.
* Not participating in any other clinical trials in the past 2 months.
* Able to understand and provide informed consent.

Exclusion Criteria:

* Presence of serious or malignant diseases (e.g., cirrhosis, heart failure, gastrointestinal tumors) that could explain dyspepsia symptoms.
* Positive for Helicobacter pylori infection based on C-13 urea breath test or gastric biopsy.
* History of gastrointestinal surgery (excluding laparoscopic and other minimally invasive surgeries).
* Recent use (within 2 weeks) of medications affecting dyspepsia, including prokinetics, proton pump inhibitors, antacids, or antidepressants.
* Presence of severe mental or physical conditions, such as dementia or illiteracy, that could interfere with study participation.
* Severe coagulation disorders.
* Substance abuse or alcohol dependence.
* Pregnant or breastfeeding women.

Where it's running

• The Third Affiliated Hospital of Zhejiang Chinese Medicinal University
  Hangzhou, None Selected, China Recruiting
• Hangzhou First People's Hospital
  Hangzhou, Zhejiang, China Recruiting
• Sir Run Run Shaw Hospital, affiliated with the Zhejiang University School of Medicine
  Hangzhou, Zhejiang, China Recruiting
• The First Affiliated Hospital of Zhejiang Chinese Medical University
  Hangzhou, Zhejiang, China Recruiting

Study contacts

• Study coordinator: Yi Liang, Doctor
• Email: liangyiwww@126.com
• Phone: +86 571 86633328

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Low-FODMAP Diet vs Standard Dietary Advice for Functional Dyspepsia

  This study tests whether a low-FODMAP diet helps adults with functional dyspepsia compared with standard dietary advice.

  Recruiting King Chulalongkorn Memorial Hospital · Bangkok, Pathumwan · NCT07925073

• Pain Reprocessing Therapy for Functional Dyspepsia

  A small pilot test to see if a psychological therapy that uses exposure techniques can lessen digestive symptoms and help daily functioning in people with functional dyspepsia.

  Recruiting Mayo Clinic · Rochester, Minnesota · NCT07838324

• Identifying Signatures of Gut Interoception in Functional Dyspepsia and Anorexia Nervosa

  This study tests how the gut-brain connection works in people with functional dyspepsia or anorexia nervosa using brain imaging.

  Recruiting Massachusetts General Hospital · Boston, Massachusetts · NCT07772167

• Prevalence and possible role of non-H. pylori Helicobacter species in gastric conditions and cancers

  Researchers will test stomach tissue from people with functional dyspeasia, various gastritis conditions, gastric cancer, and bariatric patients to see if non-H. pylori Helicobacter species are present.

  Recruiting at 3 sites Universiteit Antwerpen · Edegem and 2 other locations · NCT07770126

• Liver Fat and Scarring in People Suspected of Non-Celiac Wheat Sensitivity

  This study looks to see if people with non-celiac wheat sensitivity have liver fat or fibrosis and how this relates to IBS/FD and celiac disease.

  Recruiting at 2 sites University of Palermo · Palermo, Palermo and 1 other locations · NCT07750535

• Prevalence of Functional Dyspepsia in a Rural Community in Bangladesh

  This study tests how common functional dyspepsia is in a rural Bangladeshi community among adults who live there.

  Recruiting Bangladesh Medical University · Dhaka · NCT07694778

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.