Clinical trial Recruiting at 1 site Interventional Ages 4 to 17

Barts Children's Environmental Health Clinic

Official title: The Barts Charity Children's Environmental Health Clinic

Run by Queen Mary University of London · NCT06447974 · Data updated 2026-11-12

This service will try personal and home pollution monitoring plus tailored exposure-reduction plans for children aged 4–17 with chronic respiratory conditions to see if those steps lower their environmental exposures.

Quick facts

Study typeInterventional
Ages4 Years to 17 Years
SexAll
Enrollment200 (estimated)
SponsorQueen Mary University of London
Academic / other
Locations2 sites (London and 1 other locations)
StatusRecruiting
StartedJuly 24, 2025
Main results expectedJune 2027
Study endsJune 2027
Registry record updatedAugust 13, 2026
Trial IDNCT06447974 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Children aged 4–17 with a diagnosed chronic respiratory condition who are referred by the paediatric asthma team and whose family can consent, attend clinic visits, allow home assessments, and use the study devices and English-language materials.

Probably not a fit

Children who cannot use the monitoring devices, cannot attend the initial hospital visit, or cannot allow a home environmental assessment are unlikely to benefit from this program.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Children referred by the paediatric asthma team will have baseline clinical data taken from their records and will complete questionnaires and clinic interviews. They will wear personal environmental monitors and receive a home environmental assessment to measure exposures and identify sources. Families will be given a personalised exposure report with recommended mitigation strategies based on patterns and behaviours, then monitoring will be repeated after changes are made. The study compares different mitigation methods and stores quantitative and qualitative data securely on Queen Mary University of London/Barts Health servers.

Why it matters

Potential benefit: If successful, participants could reduce harmful pollutant exposures and related symptom triggers through tailored, practical changes at home.

How similar studies have gone: Previous home-based air-quality interventions have shown some reductions in indoor pollutant levels and symptom improvement, but combining personal exposure monitoring with tailored clinic reports is a relatively new approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Parent/Guardian able to provide written informed consent

Referral made by paediatric asthma team

Child aged 4-17 years at the time of consent to study

A diagnosis of a chronic respiratory condition (diagnosis by a medical professional)

Contactable for regular follow up by the research team

Reasonable level of English language

Ability to engage with technology and devices used in the study

Exclusion Criteria:

* Inability to use the tools and devices in the research study

Inability to visit the hospital for the initial hospital visit

Inability to allow home environmental assessment

Where it's running

  • The Royal London Hospital
    London, United Kingdom
    Recruiting
  • Queen Mary University of London
    London, United Kingdom
    Enrolling by invitation

Study contacts

  • Principal investigator: Charles S Moorcroft, MBChB — Queen Mary University of London
  • Study coordinator: Charles S Moorcroft
  • Email: c.moorcroft@qmul.ac.uk
  • Phone: 07808061892

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.