Examining health determinants and their impact on chronic diseases
Official title: Prospective Urban Rural Epidemiology Study
Run by Population Health Research Institute · NCT03225586 · Data updated 2026-11-12
This study looks at how personal choices and community factors affect heart health and other long-term illnesses to see what really impacts people's health.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 35 Years to 70 Years |
| Sex | All |
| Enrollment | 200000 (estimated) |
| Sponsor | Population Health Research Institute Academic / other |
| Locations | 34 sites (Rosario, Santa Fe Province and 33 other locations) |
| Status | Recruiting |
| Started | January 1, 2002 |
| Main results expected | December 31, 2030 |
| Study ends | December 31, 2030 |
| Registry record updated | January 31, 2024 |
| Trial ID | NCT03225586 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are consenting adults aged 35 to 70 years.
✕Probably not a fit
Patients outside the age range of 35 to 70 years will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study investigates how individual behaviors and societal factors influence health outcomes, particularly focusing on cardiovascular diseases and other non-communicable diseases. It aims to analyze the relationship between societal determinants, such as environmental factors and health policies, and the prevalence of risk factors and chronic diseases. The study will utilize both cross-sectional and prospective cohort components to gather data on health behaviors, health system quality, and genetic factors related to non-communicable diseases. By understanding these relationships, the study seeks to identify key influences on health outcomes across various socioeconomic settings.
Why it matters
Potential benefit: If successful, this study could provide insights that lead to improved public health strategies and interventions for preventing chronic diseases.
How similar studies have gone: Other studies examining the impact of societal and environmental factors on health outcomes have shown promising results, indicating that this approach is supported by previous research.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * consenting adults between 35-70 years of age Exclusion Criteria: * none
Where it's running
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Estudios Clinicos Latinoamerica ECLA
Rosario, Santa Fe Province, Argentina Recruiting -
Independent University, Bangladesh
Dhaka, Bangladesh Recruiting -
Dante Pazzanese Institute of Cardiology
São Paulo, Brazil Recruiting -
Simon Fraser University
Vancouver, British Columbia, Canada Recruiting -
Population Health Research Institute
Hamilton, Ontario, Canada Recruiting -
University of Ottawa
Ottawa, Ontario, Canada Recruiting
Show 28 more locations
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Université Laval Institut universitaire de cardiologie et de pneumologie de Québec
Québec, Quebec, Canada Recruiting -
Universidad de La Frontera
Temuco, Chile Recruiting -
State Key Laboratory of Cardiovascular Disease, Fuwai Hospital
Beijing, China Recruiting -
Fundacion Oftalmologica de Santander - FOSCAL
Floridablanca, Santander Department, Colombia Recruiting -
St John's Research Institute
Bangalore, Karnataka, India Recruiting -
Health Action by People
Thiruvananthapuram, Kerala, India Recruiting -
Eternal Heart Care Centre and Research Institute
Jaipur, Rajasthan, India Recruiting -
Madras Diabetes Research Foundation
Chennai, Tamil Nadu, India Recruiting -
Post Graduate Institute of Medical Education and Research (PGIMER)
Chandigarh, India Recruiting -
Isfahan University of Medical Sciences
Isfahan, Iran Recruiting -
Research Institute of Cardiology & Internal Diseases
Almaty, Kazakhstan Recruiting -
Kyrgyz Society of Cardiology, National Center of Cardiology and Internal Disease
Bishkek, Kyrgyzstan Recruiting -
Universiti Teknologi MARA, UCSI Universiti
Kuala Lumpur, Malaysia Recruiting -
University Kebangsaan Malaysia
Kuala Lumpur, Malaysia Recruiting -
Aga Khan University
Karachi, Pakistan Recruiting -
Birzeit University, Birzeit
Ramallah, Palestinian Territories Recruiting -
Universidad Peruana Cayetano Heredia
Lima, Peru Recruiting -
University of Philippines, Section of Adult Medicine & Medical Research Unit
Manila, Philippines Recruiting -
Wroclaw Medical University & Department of Internal Medicine
Wroclaw, Poland Recruiting -
Research Institute for Complex Issues of Cardiovascular Diseases
Kemerovo, Russia Recruiting -
King Saud University
Riyadh, Saudi Arabia Recruiting -
School of Public Health, University of the Western Cape
Bellville, South Africa Recruiting -
North-West University
Potchefstroom, South Africa Recruiting -
Sahlgrenska University Hospital/Östra Hospital
Gothenburg, Sweden Recruiting -
Pamoja Tunaweza Women Center
Moshi, Tanzania Recruiting -
Istanbul Medeniyet University
Istanbul, Turkey (Türkiye) Recruiting -
Dubai Medical University
Dubai, United Arab Emirates Recruiting -
University of Zimbabwe College of Health Sciences
Harare, Zimbabwe Recruiting
Study contacts
- Principal investigator: Salim Yusuf, DPhil — Executive Director
- Study coordinator: Sumathy Rangarajan, MSc
- Email: sumathy.rangarajan@phri.ca
- Phone: 905-521-2100
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This study is looking at around 15,000 people from a previous heart and lung health study to see how their conditions have changed over the years and to improve ways to predict and prevent heart and lung diseases.
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Barts Children's Environmental Health Clinic
This service will try personal and home pollution monitoring plus tailored exposure-reduction plans for children aged 4–17 with chronic respiratory conditions to see if those steps lower their environmental exposures.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.