Condition
Diffuse Hemispheric Glioma, H3 G34-Mutant clinical trials and research
As of November 12, 2026, Find a Trial lists 3 Diffuse Hemispheric Glioma, H3 G34-Mutant clinical trials that are recruiting, at sites in 6 countries (most in United States (2), United Kingdom (2), Australia (1)). By phase: Phase 1 (1), Phase 1/2 (1), Phase 2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 3Clinical trials
- 6Countries
Newest Diffuse Hemispheric Glioma, H3 G34-Mutant clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| 177Lu-PSMA-617 treatment for IDH‑wildtype gliomas | Phase 1 | Basking Ridge, New Jersey and 6 other locations | Recruiting | Oct 31, 2025 |
| Combination therapy for malignant brain tumors using avutometinib and defactinib | Phase 1/2 | Cambridge and 2 other locations | Recruiting | Oct 8, 2024 |
| Combining ribociclib and everolimus for treating high-grade gliomas in young patients | Phase 2 | Aurora, Colorado and 19 other locations | Recruiting | May 6, 2023 |
All recruiting trials (3)
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177Lu-PSMA-617 treatment for IDH‑wildtype gliomas
This trial will test whether the radiopharmaceutical 177Lu-PSMA-617 is safe for adults with IDH‑wildtype gliomas who have completed standard surgery and radiation.
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Combination therapy for malignant brain tumors using avutometinib and defactinib
This study is testing a new combination of two drugs, avutometinib and defactinib, to see if they can help people with advanced malignant brain tumors like glioblastoma feel better and improve their treatment options.
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Combining ribociclib and everolimus for treating high-grade gliomas in young patients
This study is testing if a combination of two drugs, ribociclib and everolimus, can help young patients with high-grade gliomas live longer and feel better after their initial treatment.
Related topics
Quick answers
How many Diffuse Hemispheric Glioma, H3 G34-Mutant clinical trials are recruiting right now?
3, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 6 countries. The most sites are in United States (2 trials), United Kingdom (2 trials), Australia (1 trial), Canada (1 trial), Germany (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1: 1, Phase 1/2: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.