Condition

Diabetic Peripheral Neuropathy clinical trials and research

• 14Clinical trials
• 10NIH research projects
• 1New in 30 days
• 7Countries

Newest Diabetic Peripheral Neuropathy clinical trials

All recruiting trials (14)

• Effects of perturbation-based balance training vs conventional balance training for reactive stepping in adults with diabetic nerve damage

  A 40-person study will test whether adding perturbation-based balance training helps adults with diabetic peripheral neuropathy react better to balance threats compared with standard balance training.

  Recruiting Lahore University of Biological and Applied Sciences · Lahore, Punjab Province · NCT07902297

• Ultrasound-guided nerve hydrodissection for diabetic leg nerves

  A single ultrasound-guided nerve hydrodissection procedure is tested to see if it helps people with diabetic lower limb entrapment neuropathy feel less pain and have better nerve function.

  Recruiting Chongqing Medical University · Chongqing, Chongqing Municipality · NCT07625020

• Shortwave therapy for diabetic peripheral neuropathy

  A one-center study will test whether shortwave therapy given for five days can improve nerve symptoms in adults with diabetic neuropathy compared to a sham treatment.

  Recruiting Chongqing Medical University · Chongqing · NCT07625007

• MinION sequencing to identify microbes in diabetic foot bone infections

  This study will test a rapid MinION DNA sequencing method to identify bacteria, fungi, and resistance genes in infected diabetic foot wounds and compare the results with standard culture.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes, Gard · NCT07391995

• Intraneural Facilitation and Otago Exercise for Diabetic Peripheral Neuropathy

  This study will test whether intraneural facilitation, the Otago exercise program, or a combination of both can improve balance, reduce neuropathic pain, and improve quality of life for people aged 50–75 with diabetic peripheral neuropathy.

  Recruiting Riphah International University · Lahore, Punjab Province · NCT07274735

• Topical Capsadyn (palmitated capsaicin) for diabetic neuropathic foot pain

  This study will test whether a topical Capsadyn cream can reduce foot pain in adults with diabetic peripheral neuropathy.

  Recruiting Early Phase 1 Carilion Clinic · Roanoke, Virginia · NCT07260656

• Melatonin for people with diabetic peripheral neuropathy

  This trial will test whether adding melatonin to usual care helps adults with type 2 diabetes who have peripheral neuropathy by reducing oxidative stress, lowering inflammation, and improving symptoms.

  Recruiting Phase 2 Ain Shams University · Cairo · NCT07036796

• Levagen+ for symptoms of diabetic peripheral neuropathy

  This study will try Levagen+, a daily supplement, to see if it reduces nerve pain and other symptoms in adults with diabetic peripheral neuropathy compared with a placebo.

  Recruiting Phase 2 RDC Clinical Pty Ltd · Fortitude Valley, Queensland · NCT07028528

• Foot sensation training to help balance, gait, and function in adults with type 2 diabetes and neuropathy

  This randomized trial tests whether foot sensory training, in addition to education, improves balance, walking, and functional ability for adults with type 2 diabetes and neuropathy.

  Recruiting Inonu University · Van · NCT06979401

• Improving walking ability in people with diabetic nerve damage using biofeedback

  This study is testing if using real-time feedback on walking can help people with diabetic nerve damage improve their walking ability and reduce the risk of serious foot problems.

  Recruiting Florida Institute for Human and Machine Cognition · Pensacola, Florida · NCT06591780

• Assessing balance control in older adults with diabetic peripheral neuropathy

  This study tests how diabetic peripheral neuropathy affects balance and muscle activity in adults over 50 to see if it increases their risk of falling.

  Recruiting University of Texas at Austin · Austin, Texas · NCT06544876

• Validating an Arabic version of a quality of life questionnaire for diabetic neuropathy patients

  This study is trying to create and test an Arabic version of a quality of life questionnaire for Arabic-speaking patients with diabetic neuropathy to make sure it works well for them.

  Recruiting Cairo University · Cairo, Giza Governorate · NCT06483620

• Using spinal cord stimulation to treat diabetic peripheral neuropathy

  This study is testing if spinal cord stimulation can help people with diabetic peripheral neuropathy feel less pain and improve their nerve health.

  Recruiting Ohio State University · Columbus, Ohio · NCT06287736

• Walking and foot-pressure biofeedback for people with diabetic peripheral neuropathy

  This project will test whether real-time biofeedback about foot pressure and push-off can change walking patterns and improve walking function in adults with diabetic peripheral neuropathy.

  Recruiting Florida Institute for Human and Machine Cognition · Pensacola, Florida · NCT05965336

NIH-funded research (10)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Gut bacterial vesicles and diabetic nerve damage

  This work looks at whether tiny particles released by gut bacteria can protect nerves and ease numbness and pain in people with diabetic peripheral neuropathy.

  NIH research Henry Ford Health + Michigan State University Health Sciences · East Lansing, United States · NIH-11286790

• Restoring sensation in amputated limbs for veterans with diabetic neuropathy

  This study is looking to help veterans who have lost lower limbs due to diabetic peripheral neuropathy by using special electrodes to create sensations that feel like they're coming from their missing foot, which could improve their daily activities and overall limb health.

  NIH research Louis Stokes Cleveland VA Medical Center · Cleveland, United States · NIH-11262790

• Wearable vibration to improve movement and reduce pain in diabetic nerve damage

  A wearable vibration device is tested for four weeks to help adults with diabetic peripheral neuropathy walk better and experience less pain.

  NIH research University of Florida · Gainesville, United States · NIH-11226229

• Improving walking and reducing foot pressure for people with diabetic nerve damage

  This project tries real-time biofeedback to change how adults with diabetic peripheral neuropathy walk so they have lower harmful foot pressure and better walking speed.

  NIH research Florida Institu /human/machine Cognition · Pensacola, United States · NIH-11168786

• Exploring how gut bacteria affect nerve damage in diabetes

  This study is looking at how tiny particles from gut bacteria might help protect nerves in people with diabetic peripheral neuropathy, which is a common issue for those with diabetes, and it hopes to find new ways to improve nerve health through better gut health.

  NIH research Henry Ford Health + Michigan State University Health Sciences · East Lansing, United States · NIH-11046549

• Investigating how tau phosphorylation affects nerve damage in diabetes

  This study is looking into how problems with insulin and a protein called tau affect nerve health in people with Type 1 Diabetes, with the hope of finding new ways to ease the pain and improve life for those dealing with diabetic nerve issues.

  NIH research University of Tx Md Anderson Can Ctr · Houston, United States · NIH-10980022

• New treatment for painful diabetic nerve damage using cannabidiol and palmitoylethanolamide tablets

  This study is testing a new type of tablet that combines two ingredients to help relieve pain for people with painful diabetic peripheral neuropathy, aiming to provide relief without the side effects of regular pain medications.

  NIH research Pure Green Pharmaceuticals, INC. · West Bloomfield, United States · NIH-10932267

• Improving access to diabetic foot exams for underserved communities

  This study is working on a simple and affordable way to help people with diabetes, especially in underserved communities, by using smartphones to spot early signs of nerve damage in their feet, so they can get the care they need sooner.

  NIH research Visionquest Biomedical INC · Albuquerque, United States · NIH-10918922

• Investigating the role of omega-3 fatty acids in treating nerve damage from diabetes

  This study is looking at whether omega-3 fatty acids, like those found in fish oil, can help repair nerve damage in veterans with type 2 diabetes who have diabetic peripheral neuropathy, and it hopes to find new ways to improve their nerve health.

  NIH research Iowa City VA Medical Center · Iowa City, United States · NIH-10854778

• Exosomes from Schwann cells may help improve nerve function in diabetic mice

  This study is looking at how tiny particles from special cells can help improve nerve health in mice with diabetic nerve damage, and it hopes to show that these particles can make nerves work better without changing blood sugar levels.

  NIH research Henry Ford Health System · Detroit, United States · NIH-10643939

Related topics

Quick answers

How many Diabetic Peripheral Neuropathy clinical trials are recruiting right now?

14, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in United States (5 trials), Pakistan (2 trials), Egypt (2 trials), China (2 trials), Australia (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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