Improving walking ability in people with diabetic nerve damage using biofeedback

Innovative Multi-Variable Biofeedback for Improving Gait Performance in Individuals With Diabetic Peripheral Neuropathy

Not applicable Interventional Florida Institute for Human and Machine Cognition · NCT06591780

This study is testing if using real-time feedback on walking can help people with diabetic nerve damage improve their walking ability and reduce the risk of serious foot problems.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment25 (estimated)
Ages45 Years to 90 Years
SexAll
SponsorFlorida Institute for Human and Machine Cognition Academic / other
Locations1 site (Pensacola, Florida)
Trial IDNCT06591780 on ClinicalTrials.gov

What this trial studies

This study aims to enhance gait performance in individuals suffering from Diabetic Peripheral Neuropathy (DPN) by utilizing innovative biofeedback techniques. Participants will undergo clinical evaluations and 3-Dimensional gait analysis on a treadmill, receiving real-time visual and auditory feedback on their walking mechanics. The study focuses on understanding the biomechanical factors affecting plantar pressure and propulsion during gait, with the goal of developing personalized biofeedback interventions to improve walking function and reduce the risk of complications such as ulcers and amputations.

Who should consider this trial

Good fit: Ideal candidates are individuals diagnosed with diabetes mellitus and diabetic peripheral neuropathy who can walk independently without assistive devices.

Not a fit: Patients with severe cognitive or visual impairments, active ulcers, or significant orthopedic issues unrelated to diabetes may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve walking ability and quality of life for patients with diabetic peripheral neuropathy.

How similar studies have performed: While the use of biofeedback in rehabilitation is promising, this specific multi-variable approach in the context of diabetic peripheral neuropathy is relatively novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Able to walk 10-meters independently without an assistive device
* Sufficient cardiovascular and musculoskeletal health to walk on a treadmill for 6 minutes at a self-selected speed
* Diagnosis of diabetes mellitus
* Diagnosis of diabetic peripheral neuropathy by a physician
* Foot examination within the past 6 months documenting ambulatory status
* Physician clearance

Exclusion Criteria:

* History of amputation
* Active ulceration
* Medial column deformity
* Severe cognitive impairment (MoCA \< 10)
* Severe visual impairment
* History of Charcot osteoarthropathy
* History of posterior muscle group lengthening
* History of lower extremity joint replacement
* History of lower extremity and/or foot surgery affecting walking mechanics
* Orthopaedic problems of the lower limbs or spine due to other medical conditions (not diabetes or DPN) that limit walking or cause pain during walking
* Improper footwear for walking and community ambulation
* Cardiovascular or medical condition affecting ability to walk safely
* History of unexplained dizziness or fainting in the past 2 months
* Allergy to adhesive tape or rubbing alcohol

Where this trial is running

Pensacola, Florida

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Diabetic Peripheral NeuropathyDiabetes Mellitusanterior ground reaction forcebiofeedback-induced changes in plantar pressurediabetic peripheral neuropathy
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.