Condition

Chronic Stroke clinical trials and research

• 23Clinical trials
• 15NIH research projects
• 9Countries

Newest Chronic Stroke clinical trials

All recruiting trials (23)

• Task-oriented training plus NDT vs high-intensity gait training plus NDT for chronic stroke walking

  In adults with chronic stroke, the study tests whether adding structured, high-repetition task-oriented training or high-intensity gait training to neurodevelopmental treatment improves walking ability more than NDT alone.

  Recruiting Istanbul University - Cerrahpasa · Bingoel, Center · NCT07725211

• Action Observation Therapy for Chronic Stroke via Telerehabilitation

  This study tests whether watching and then imitating simple daily actions through a home-based telerehabilitation program improves hand function and quality of life for adults with chronic stroke.

  Recruiting at 2 sites Karabuk University · Karabük, Merkez and 1 other locations · NCT07631182

• Unimanual vs. Bimanual Action Observation Therapy for Chronic Stroke Upper-Limb Recovery

  This study tests whether action observation therapy using one hand or both hands improves arm function and daily living in adults with chronic stroke.

  Recruiting Karabuk University · Karabük, Merkez · NCT07631169

• CONUT score and its link to balance and everyday function after chronic stroke.

  This will see if the CONUT nutritional score and measures of muscle and bone relate to balance and daily function in adults at least six months after a stroke.

  Recruiting Marmara University · Istanbul, Pendik · NCT07468110

• Comparing constraint-induced movement therapy and bilateral training to improve arm and hand use after chronic stroke

  This tests whether restraining the unaffected arm plus electrical stimulation or training both arms together with electrical stimulation better reduces wrist tightness and improves hand use in adults with chronic stroke.

  Recruiting University of Lahore · Lahore, Punjab Province · NCT07378774

• Using vibration and low‑intensity electrical pulses to improve arm proprioception after stroke

  This project tests whether a wearable device that delivers gentle vibrations and low‑intensity electrical pulses can improve arm position and movement sense in people with chronic stroke, with healthy volunteers included for comparison.

  Recruiting Universidad Rey Juan Carlos · Móstoles, Madrid · NCT07073989

• Psilocybin to reopen brain plasticity after chronic stroke

  This trial will test whether a supervised dose of psilocybin is safe and can help reopen brain plasticity in adults who had an ischemic or hemorrhagic stroke at least 12 months ago.

  Recruiting Phase 1 Johns Hopkins University · Baltimore, Maryland · NCT07053917

• Improving leg function in stroke survivors using exercise and electrical stimulation

  This study is testing if a mix of light weight training and electrical stimulation can help stroke survivors improve their leg strength and mobility.

  Recruiting The Hong Kong Polytechnic University · Hong Kong · NCT06973590

• Motor imagery training to improve upper limb strength in chronic stroke patients

  This study tests if combining motor imagery training with regular physical therapy can help people who had a stroke improve their arm strength and coordination.

  Recruiting Foundation University Islamabad · Islamabad · NCT06945185

• Comparing robotic rehabilitation and occupational therapy for upper limb recovery after stroke

  This study is testing whether robotic therapy or regular occupational therapy helps stroke survivors improve the use of their affected arm and hand.

  Recruiting University of Florence · Florence, Italy · NCT06884553

• Transcranial direct current stimulation to improve walking in stroke patients

  This study is testing if a brain stimulation technique can help stroke survivors walk better while doing two things at once.

  Recruiting The Hong Kong Polytechnic University · Hong Kong, China · NCT06818240

• Improving turning and balance in post-stroke patients through specialized training

  This study is testing a new training program to see if it can help people recovering from a stroke improve their balance and turning ability.

  Recruiting Foundation University Islamabad · Islamabad, Punjab Province · NCT06749002

• Robot-assisted gait training for people with chronic stroke

  This study tests if robot-assisted walking training can help people who have had a stroke improve their walking, balance, and muscle strength.

  Recruiting Biruni University · Istanbul, Zeytinburnu · NCT06746415

• Comparing two rehabilitation programs for balance and walking in stroke patients

  This study is testing which rehabilitation program, Motor Relearning or Proprioceptive Neuromuscular Facilitation, helps stroke patients improve their balance and walking better after six months of recovery.

  Recruiting Foundation University Islamabad · Islamabad · NCT06674590

• Using non-invasive nerve stimulation to improve language recovery in stroke survivors with aphasia

  This study is testing if a new non-invasive treatment using nerve stimulation can help stroke survivors with long-term language difficulties improve their communication skills when combined with speech therapy.

  Recruiting Sheffield Teaching Hospitals NHS Foundation Trust · Sheffield · NCT06403475

• Personalized brain stimulation for stroke recovery

  This study is testing if a personalized brain stimulation treatment can help people who have had a stroke recover better and improve movement in their affected arm during therapy.

  Recruiting The Methodist Hospital Research Institute · Houston, Texas · NCT06286800

• Magnetic brain stimulation and computer training for stroke rehabilitation

  This study is testing if combining magnetic brain stimulation with computer training can help people recover their movement skills after a stroke.

  Recruiting Max Planck Institute for Human Cognitive and Brain Sciences · Leipzig, Saxony · NCT06116942

• Combining touch-based sensory and movement training to improve arm function after chronic stroke

  This trial tests whether combining touch-based sensory training with arm movement exercises helps people with chronic stroke regain arm function better than sensory training or movement training alone.

  Recruiting National Taiwan University Hospital · Taipei, Taiwan · NCT06057584

• Home-based functional electrical stimulation training for chronic stroke patients

  This study is testing if a home-based electrical stimulation program can help people who have had a stroke improve their walking and balance over 12 weeks.

  Recruiting University of Illinois Chicago · Chicago, Illinois · NCT05849532

• Using electrical stimulation to improve cognitive and motor function in stroke patients

  This study is testing if two types of electrical stimulation can help improve thinking and movement skills in people who have had a stroke.

  Recruiting The Hong Kong Polytechnic University · Hong Kong · NCT05615610

• Improving hand and arm recovery after stroke using electrical stimulation

  This study is testing if using electrical stimulation along with rehabilitation can help people who have had a stroke regain movement in their hands and arms.

  Recruiting University of Washington · Seattle, Washington · NCT05591196

• Using a wearable exoskeleton to help stroke patients regain arm movement

  This study is testing if using a special arm device called MyoPro along with therapy can help stroke patients regain movement in their arms better than therapy alone.

  Recruiting VA Office of Research and Development · Cleveland, Ohio · NCT05296408

• Using electrical stimulation to improve balance and reduce fall risk in stroke patients

  This study is testing if using electrical stimulation on leg muscles can help stroke patients improve their balance and reduce their risk of falling.

  Recruiting University of Illinois Chicago · Chicago, Illinois · NCT04957355

NIH-funded research (15)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Non-Invasive Brain Stimulation to Improve Movement After Stroke

  A new non-invasive technique called kilohertz Transcranial Magnetic Perturbation (kTMP) is being tested to improve arm movement in people who have chronic stroke.

  NIH research Magnetic Tides, INC. · El Cerrito, United States · NIH-11397366

• Instrumented brain organoids for chronic stroke repair

  A study exploring how tiny, living brain tissue 3D «organoids» attached to flexible, safer electrodes could help restore brain function after a stroke.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11372447

• Multisensory support to improve standing balance after stroke

  This project uses extra sensory feedback to help people with long-term stroke improve their standing balance.

  NIH research Ralph H Johnson VA Medical Center · Charleston, United States · NIH-11310730

• Biomarkers to predict who benefits from high‑intensity aerobic training after chronic stroke

  This project looks at blood and brain signals to figure out who with long‑term leg weakness after stroke will get better with high‑intensity aerobic training.

  NIH research Veterans Health Administration · Decatur, UNITED STATES · NIH-11306586

• Improving hand function in stroke survivors with muscle activation techniques

  This study is looking at how special techniques can help people who have had a moderate-to-severe stroke improve their hand use, making it easier for them to do everyday tasks and regain their independence.

  NIH research University of Utah · Salt Lake City, United States · NIH-11172028

• Understanding balance control while walking in people with chronic stroke

  This study looks at how people who have had a stroke keep their balance while walking in tricky situations, and it aims to find ways to help them improve their walking and balance during recovery.

  NIH research University of Delaware · Newark, UNITED STATES · NIH-11064291

• Training to improve balance and reduce falls in people after a stroke

  This study is all about helping people who have had a stroke improve their balance and lower their chances of falling by trying out new training methods that focus on specific balance issues.

  NIH research Medical University of South Carolina · Charleston, United States · NIH-11061902

• Exploring how social participation and psychological flexibility affect chronic stroke survivors

  This study is looking at how getting involved in social activities can help stroke survivors feel better and connect with others, and it’s testing a friendly approach that combines practice with support to help them overcome any fears that might hold them back.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11054926

• Improving balance for people with chronic stroke using multisensory feedback

  This study is testing a new way to help people who have had a stroke improve their balance by using special feedback that helps them better understand their body movements, making it easier for them to stay steady on their feet.

  NIH research Ralph H Johnson VA Medical Center · Charleston, United States · NIH-11034094

• Identifying factors that help stroke survivors respond to exercise training

  This study is looking to find out which stroke survivors might get the most help from a special type of exercise called high-intensity interval training to walk better, using certain biological markers to create personalized exercise plans just for them.

  NIH research Veterans Health Administration · Decatur, UNITED STATES · NIH-11030787

• Using music to help mental health recovery after stroke

  This study is exploring whether listening to music can help stroke survivors feel better and reduce anxiety and depression as they recover.

  NIH research New York University · New York, United States · NIH-10973344

• Exploring how vagus nerve stimulation can improve movement after chronic stroke

  This study is looking at how using a special device to stimulate a nerve in the neck, along with rehabilitation exercises, can help people who have had a stroke regain better movement in their arms and hands.

  NIH research New York University School of Medicine · New York, United States · NIH-10827024

• Improving walking activity and confidence in individuals with chronic stroke

  This study is for people who have had a stroke and want to feel more confident and active while walking and doing daily tasks without the fear of falling; it will help find out what specific balance skills they need to work on so they can get the right support to improve their walking and confidence in everyday life.

  NIH research University of Delaware · Newark, UNITED STATES · NIH-10786222

• A remote system to help stroke patients regain hand function

  This study is testing a new way for people who have had a stroke to do their hand rehabilitation at home using a special device that reads brain signals and helps them practice with a robotic hand, making it easier for them to improve their hand function.

  NIH research Neurolutions, INC · Van Nuys, UNITED STATES · NIH-10690004

• Combining language therapy with robot-assisted arm treatment for stroke survivors

  This study is exploring a new way to help stroke survivors who have trouble with speaking and moving their arms by combining computer-based language therapy with robot-assisted arm exercises, making recovery easier and more effective for them.

  NIH research New York University · New York, United States · NIH-10640826

Related topics

Quick answers

How many Chronic Stroke clinical trials are recruiting right now?

23, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 9 countries. The most sites are in United States (6 trials), Turkey (Türkiye) (5 trials), Pakistan (4 trials), Hong Kong (3 trials), Spain (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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