CONUT score and its link to balance and everyday function after chronic stroke.
Evaluation Of The Relationship Between The Conut Score And Balance And Functional Status In Patients With Chronic Stroke
Marmara University · NCT07468110
This will see if the CONUT nutritional score and measures of muscle and bone relate to balance and daily function in adults at least six months after a stroke.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 47 (estimated) |
| Ages | 18 Years to 85 Years |
| Sex | All |
| Sponsor | Marmara University (other) |
| Drugs / interventions | radiation |
| Locations | 1 site (Istanbul, Pendik) |
| Trial ID | NCT07468110 on ClinicalTrials.gov |
What this trial studies
This observational study will enroll adults at least six months after ischemic or hemorrhagic stroke to measure CONUT score, mid‑upper arm circumference, rectus femoris muscle thickness by ultrasound, and bone mineral density. Balance and mobility will be evaluated with the Tinetti Performance‑Oriented Mobility Assessment and ambulation level, while functional status and quality of life will be captured using stroke‑specific scales such as the SS‑QOL. The study analyzes correlations between nutritional, muscle, and bone measures and balance, functional status, and stroke‑specific quality of life. All assessments are performed in person at a single center (Marmara University Pendik Training and Research Hospital).
Who should consider this trial
Good fit: Adults (≥18 years) with ischemic or hemorrhagic stroke at least six months earlier who are clinically stable, can stand or ambulate (with an aid if needed), and can complete assessment scales are the ideal candidates.
Not a fit: People in the acute/subacute phase (<6 months), those with severe cognitive impairment or aphasia, or those with other major neurological or orthopedic conditions are unlikely to receive benefit from participation.
Why it matters
Potential benefit: If positive, the findings could help clinicians identify nutritional or muscle‑loss markers to target for interventions that improve balance and independence after chronic stroke.
How similar studies have performed: Previous research has linked poor nutritional status and reduced muscle mass to worse balance and function after stroke, though combining CONUT, ultrasound muscle measures, and bone density in chronic stroke populations is less commonly reported.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Being 18 years of age or older * Having a diagnosis of ischemic or hemorrhagic stroke * At least 6 months having elapsed since the stroke event (chronic phase) * Being clinically stable * Being able to participate in standing and balance assessments (walking with an assistive device is acceptable) * Having sufficient cognitive capacity to understand and respond to the assessment scales used in the study * Voluntarily agreeing to participate in the study and providing written informed consent Exclusion Criteria: * Acute or subacute stroke phase (\< 6 months) * Inability to administer assessment scales due to severe cognitive impairment or aphasia * Presence of other neurological disorders that may significantly affect balance and functional status (e.g., Parkinson's disease, multiple sclerosis, peripheral neuropathy) * Significant orthopedic conditions unrelated to stroke (e.g., advanced hip or knee osteoarthritis, lower extremity amputation) * Presence of active infection, malignancy, or systemic inflammatory disease (as these conditions may affect the CONUT score) * Cerebellar localization of the cerebrovascular event * History of major surgery or intensive care unit admission within the past 3 months * Inability to safely perform balance tests due to severe visual or hearing impairment * Patients with incomplete laboratory data or insufficient information to calculate the CONUT score
Where this trial is running
Istanbul, Pendik
- Marmara University Faculty of Medicine Pendik Training and Research Hospital — Istanbul, Pendik, Turkey (Türkiye) (RECRUITING)
Study contacts
- Study coordinator: Fatma B Akdağ
- Email: fatma.betul820@gmail.com
- Phone: +90 537 452 96 60
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Chronic Stroke, CONUT Score, Balance Assessment, Functional Status, Tinetti Performance-Oriented Mobility Assessment, Stroke-Specific Quality of Life Scale, Rectus femoris muscle thickness, Mid-upper arm circumference measurement