Unimanual vs. Bimanual Action Observation Therapy for Chronic Stroke Upper-Limb Recovery
Official title: Investigation of the Effects of Action Observation Therapy Including Unimanual and Bimanual Activities on Upper Extremity Functions, Activities of Daily Living, and Quality of Life in Chronic Stroke
Run by Karabuk University · NCT07631169 · Data updated 2026-11-12
This study tests whether action observation therapy using one hand or both hands improves arm function and daily living in adults with chronic stroke.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 45 (estimated) |
| Sponsor | Karabuk University Academic / other |
| Locations | 1 site (Karabük, Merkez) |
| Status | Recruiting |
| Started | May 18, 2026 |
| Main results expected | June 22, 2026 |
| Study ends | May 18, 2027 |
| Registry record updated | June 9, 2026 |
| Trial ID | NCT07631169 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults over 18 with left-hemiparetic stroke, at least six months post-stroke, and sufficient motor, cognitive, and functional capacity to participate.
✕Probably not a fit
Patients with severe spasticity, neglect, or cognitive impairment that prevents participation may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
In chronic stroke, upper-limb impairment limits daily activities and quality of life. The study compares two Action Observation Therapy approaches—unimanual and bimanual—delivered with observation of relevant tasks followed by imitation, plus conventional physiotherapy. Outcomes focus on upper-extremity function, daily living activities, and quality of life. The trial aims to determine which hand-use approach yields greater improvement over time. Participants will be adults with left-hemiparetic stroke, at least six months post-stroke, and meeting specific functional and cognitive criteria.
Why it matters
Potential benefit: If successful, patients could experience greater gains in arm function and independence in daily activities.
How similar studies have gone: Previous research supports action observation approaches for motor learning, but direct comparison of unimanual vs. bimanual methods in chronic stroke is less established.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Being over 18 years of age, * Diagnosis of left hemiparetic stroke, * Having passed between 6 months since the onset of stroke, * Being in stage 4 or 5 of the hand and stage 4, 5 or 6 of the upper extremity --according to Brunnstrom staging, * Being able to sit on a chair for 30 minutes without support (patients who scored 20 or more points in total from the Trunk Impairment Scale), * Scoring 24 or more points from the Mini Mental Test Exclusion Criteria: * Unwillingness to participate in the study, * Having spasticity that prevents grasping and releasing an object (levels 3 and 4 on the Modified Ashworth Scale), * Having a contracture in any of the affected upper extremity joints, * Having severe neglect disorder (scoring 21 or higher on the Catherine Bergego Scale), * Having impaired cooperation, compliance, and behavior during the administration of tests used to obtain data, * Having a mental impairment that prevents communication and following basic commands (scoring less than 24 on the Mini-Mental Test), * Having additional neurological and/or orthopedic problems that may affect motor performance and sitting balance, * Having severe visual and hearing problems (if any, these problems not corrected with assistive devices such as glasses, contact lenses, hearing aids, etc.)
Where it's running
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Mustafa KAVAK
Karabük, Merkez, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Mustafa KAVAK, Phd
- Email: mustafakavak@karabuk.edu.tr
- Phone: +905065089564
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.