Identifying factors that help stroke survivors respond to exercise training
What makes a responder, a responder? Biomarkers to help identify responders and resistors to high-intensity interval training for lower extremity chronic stroke
This study is looking to find out which stroke survivors might get the most help from a special type of exercise called high-intensity interval training to walk better, using certain biological markers to create personalized exercise plans just for them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Health Administration NIH-funded |
| Lab location | 1 site (Decatur, UNITED STATES) |
| Project ID | NIH-11030787 on NIH RePORTER |
What this research studies
This research investigates how to predict which chronic stroke survivors will benefit from high-intensity interval training to improve their walking ability. By focusing on biomarkers like lactate and neurotransmitters, the study aims to develop a predictive model that can guide personalized exercise interventions. This approach seeks to enhance rehabilitation outcomes by tailoring exercise programs to individual patient needs based on their biological responses. The ultimate goal is to improve functional recovery in stroke patients through targeted aerobic exercise.
Who could benefit from this research
Good fit: Ideal candidates for this research are chronic subcortical stroke survivors who experience difficulty walking and are over 21 years old.
Not a fit: Patients who have not experienced a stroke or those with conditions that severely limit their ability to participate in exercise may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective rehabilitation strategies for stroke survivors, enhancing their mobility and quality of life.
How similar studies have performed: Previous research has shown promise in using biomarkers to tailor rehabilitation strategies, suggesting that this approach could yield significant insights.
Where this research is happening
Decatur, UNITED STATES
- Veterans Health Administration — Decatur, United States (Active)
Researchers
- Principal investigator: Krishnamurthy, Lisa C. — Veterans Health Administration
- Study coordinator: Krishnamurthy, Lisa C.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.