Using vibration and low‑intensity electrical pulses to improve arm proprioception after stroke

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study applies afferent stimulation—mechanical vibrations combined with low‑intensity electrical currents—to deliver enhanced proprioceptive feedback to the upper limb. Sessions will compare responses in people with chronic stroke and in healthy volunteers to characterize device effects and baseline sensory function. Eligible stroke participants have chronic ischemic or hemorrhagic stroke with mild‑to‑moderate upper‑limb impairment and sufficient cognition (MMSE >24). Outcome measures will include standardized upper‑limb motor and sensory scores such as the Fugl‑Meyer upper‑limb sections and functional performance tests conducted at Universidad Rey Juan Carlos.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* For healthy subjects:

  1. No neurological or orthopedic conditions affecting upper limb movement.
  2. No surgical interventions on the upper limbs within the past 6 months.
  3. General physical condition adequate to perform the session.
  4. Cognitive abilities sufficient to understand and carry out the experimental procedure.
* For stroke survivors:

  1. Ischemic or hemorrhagic stroke resulting in motor impairments in the upper limb.
  2. Chronic stroke condition.
  3. Subjects with sufficient cognitive abilities to follow instructions and actively participate in the therapy.
  4. Mini-Mental State Examination (MMSE) score \> 24.
  5. Subjects presenting hemiparesis and mild-to-moderate impairment in the upper limb (score on the Fugl-Meyer Motor Assessment for the upper limb, sections A-D, between 35 and 53 points). The maximum score on the FM scale is 66, with the following severity classifications:
* 0-15: severe impairment
* 16-34: moderate-to-severe impairment
* 35-53: mild-to-moderate impairment
* 54-66: mild impairment 6. Subjects presenting upper limb hypertonia with a score below 3 on the Modified Ashworth Scale.

  7\. Subjects who have signed the informed consent document to voluntarily participate in the experiments.

Exclusion Criteria:

1. Acute musculoskeletal disorders.
2. Peripheral vascular diseases.
3. Acute cardiopulmonary conditions.
4. Acute neurological disorders.
5. Restricted mobility of upper limb joints due to any cause.
6. Pain as a cause of impaired upper limb mobility.

Where it's running

• Universidad Rey Juan Carlos
  Móstoles, Madrid, Spain Recruiting

Study contacts

• Study coordinator: Julio S. Lora Millán, PhD in Automation and Robotics
• Email: julio.lora@urjc.es
• Phone: 914880000

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.