Task-oriented training plus NDT vs high-intensity gait training plus NDT for chronic stroke walking

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This assessor-blinded randomized trial compares three approaches for improving walking after chronic stroke: neurodevelopmental treatment (NDT) alone, NDT plus high-repetition task-oriented training, and NDT plus high-intensity gait training. Forty-five participants (15 per group) receive 75 minutes of therapy per session, three days per week for eight weeks, at two sites in Bingöl, Türkiye. Primary outcome is the 6-Minute Walk Test, with secondary measures of functional mobility such as the Timed Up and Go, Dynamic Gait Index, and 10-Meter Walk Test. The study aims to determine if adding intensity- or repetition-based training to conventional NDT yields greater gains in walking capacity than NDT alone.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosis of first-ever unilateral stroke (ischemic or hemorrhagic) confirmed by clinical and/or radiological findings
* Time since stroke onset of at least 6 months (chronic phase)
* Age between 18 and 75 years
* Ability to walk at least 10 meters independently, with or without an assistive device
* Functional Ambulation Category (FAC) score of 3 or higher
* Sufficient cognitive ability to understand and follow instructions (Mini-Mental State Examination score ≥ 24)
* Willingness to participate and provision of written informed consent

Exclusion Criteria:

* Recurrent stroke or bilateral hemispheric involvement
* Unstable cardiovascular disease or other medical conditions contraindicating high-intensity exercise
* Severe lower extremity spasticity interfering with gait training (Modified Ashworth Scale score \> 3)
* Orthopedic, rheumatological, or other neurological conditions affecting gait
* Severe visual or vestibular impairment
* Severe aphasia or cognitive impairment preventing participation in training or assessments
* Participation in another structured rehabilitation or exercise program during the study period
* Botulinum toxin injection to the lower extremity within the last 6 months

Where it's running

• Bingol State Hospital - City: Bingöl, Country: Türkiye (listede "Turkey" olarak geçebilir), Zip: 12000
  Bingoel, Center, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Emrah Zirek, Ph. D.
• Email: zireke@gmail.com
• Phone: +904262160012

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.