Clinical trial Recruiting at 1 site Interventional Ages 20 and up

Combining touch-based sensory and movement training to improve arm function after chronic stroke

Official title: The Neural Mechanism and Efficacy of Somatosensory Motor Intergration Training on the Upper Extremity Somatosensory Motor Function in Patients With Chronic Stroke.

Run by National Taiwan University Hospital · NCT06057584 · Data updated 2026-11-12

This trial tests whether combining touch-based sensory training with arm movement exercises helps people with chronic stroke regain arm function better than sensory training or movement training alone.

Quick facts

Study typeInterventional
Ages20 Years and up
SexAll
Enrollment153 (estimated)
SponsorNational Taiwan University Hospital
Academic / other
Locations1 site (Taipei, Taiwan)
StatusRecruiting
StartedOctober 11, 2023
Main results expectedJuly 31, 2026
Study endsJuly 31, 2026
Registry record updatedMarch 3, 2026
Trial IDNCT06057584 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults (≥20 years) at least six months after a stroke with upper-limb Brunnstrom stage III–V, self- or therapist-identified somatosensory impairment, and no severe spasticity (Modified Ashworth Scale ≤2).

Probably not a fit

Patients with significant cognitive impairment (MoCA <20), severe aphasia, hemineglect, major psychiatric disorders, substance abuse, severe upper-limb musculoskeletal problems, or other contraindications are unlikely to benefit or be eligible.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized interventional trial will compare three approaches for people with chronic stroke: somatosensory-motor integration training, pure somatosensory training, and pure motor training. Participants are adults at least six months post-stroke with persistent upper-limb impairment and measurable somatosensory deficits. The interventions are delivered in person at a single center and outcomes will focus on upper-limb functional recovery and related neural changes. The design aims to determine whether combining sensory and motor practice produces greater functional gains than either approach alone.

Why it matters

Potential benefit: If successful, the combined training could lead to better arm function and greater independence in daily activities for people living with chronic stroke.

How similar studies have gone: Smaller prior studies have shown that somatosensory or motor training can improve motor performance, but combined somatosensory-motor approaches have limited and low-quality evidence so far.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Age ≥ 20.
2. Diagnosed with stroke.
3. Stroke duration ≥ 6 months.
4. Upper limb Brunnstrom stage III-V.
5. No severe muscle spasticity (Modified Ashworth Scale ≤ 2) in all segments of the affected upper limb.
6. Self-perceived or therapist-assessed somatosensory impairment.

Exclusion Criteria:

1. Significant cognitive impairment (Montreal Cognitive Assessment \< 20).
2. Severe mental disorders (e.g., schizophrenia, major depression).
3. Substance abuse or alcoholism.
4. Claustrophobia.
5. Severe aphasia affecting comprehension and clear expression of somatosensory information.
6. Hemineglect.
7. Other muscle or joint problems affecting upper limb function (e.g., contractures, rheumatoid arthritis, myositis ossificans).
8. Concurrent participation in other somatosensory or motor therapy studies.

Where it's running

  • National Taiwan University Hospital
    Taipei, Taiwan, Taiwan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.