Condition

Bladder Pain Syndrome clinical trials and research

• 16Clinical trials
• 9NIH research projects
• 5Countries

Newest Bladder Pain Syndrome clinical trials

All recruiting trials (16)

• Aerobic Exercise and Massage for Painful Bladder Syndrome in Women

  This study tests whether adding aerobic exercise and connective tissue massage to patient education helps reduce bladder pain and improve symptoms for women with bladder pain syndrome.

  Recruiting Hacettepe University · Ankara, Ankara · NCT07839689

• Neovasculgen for interstitial cystitis with Hunner's lesions

  This study will test whether Neovasculgen can reduce bladder scarring and prevent bladder shrinkage in women with interstitial cystitis and Hunner's lesions.

  Recruiting Phase 2/3 JSC NextGen · Moscow · NCT07459790

• Comparing Botox injections to conservative management for female sexual function in bladder pain syndrome

  This study tests whether Botox injections can improve sexual function in women with bladder pain syndrome better than standard treatment options.

  Recruiting Walter Reed National Military Medical Center · Bethesda, Maryland · NCT06729151

• Evaluating a catheter-free method for bladder medication delivery

  This study is testing a new way to deliver bladder medication without a catheter to see if it’s more comfortable and safer for people with conditions like interstitial cystitis and recurrent urinary tract infections.

  Recruiting at 2 sites Jahn Ferenc South Pest Teaching Hospital · Budapest and 1 other locations · NCT06719232

• Treatment of bladder pain using VNX001

  This study is testing a new treatment called VNX001 to see if it can help people with moderate to severe bladder pain feel better.

  Recruiting at 2 sites Phase 2 Vaneltix Pharma, Inc. · Tucson, Arizona and 4 other locations · NCT06394830

• Using Botox to treat overactive bladder while preventing urinary tract infections

  This study is testing if Botox injections for overactive bladder can be safely combined with a specific antibiotic to help prevent urinary tract infections in women.

  Recruiting Phase 4 Walter Reed National Military Medical Center · Bethesda, Maryland · NCT06387329

• Acupuncture for treating bladder pain syndrome in women

  This study is testing if acupuncture, along with some behavior changes, can help women with bladder pain syndrome feel better when other treatments haven't worked.

  Recruiting University Hospitals Cleveland Medical Center · Cleveland, Ohio · NCT06366269

• Assessing pain types in treating bladder pain syndrome

  This study is trying to see how different types of bladder pain affect how well people with bladder pain syndrome respond to pelvic floor physical therapy and cognitive-behavioral therapy.

  Recruiting Vanderbilt University Medical Center · Franklin, Tennessee · NCT06299683

• Investigating brain imaging and symptoms in bladder pain syndrome

  This study is testing how brain scans relate to the symptoms of bladder pain syndrome to help understand the condition better for future treatments.

  Recruiting RenJi Hospital · Shanghai, Shanghai Municipality · NCT06294951

• Exploring nerve stimulation therapy for bladder pain syndrome in women

  This study is testing if a new nerve stimulation therapy can help women with bladder pain syndrome feel less pain compared to a placebo treatment.

  Recruiting Walter Reed National Military Medical Center · Bethesda, Maryland · NCT06204874

• Evaluating VNX001 for bladder pain relief in patients with interstitial cystitis

  This study is testing if a new treatment called VNX001 can help relieve bladder pain in people with interstitial cystitis better than its individual ingredients or a placebo.

  Recruiting at 11 sites Phase 2 Vaneltix Pharma, Inc. · Escondido, California and 13 other locations · NCT05737121

• Evaluating electroacupuncture for bladder pain syndrome

  This study is testing if electroacupuncture can help people with bladder pain syndrome feel better compared to medication and a fake treatment.

  Recruiting The Third Affiliated hospital of Zhejiang Chinese Medical University · Hangzhou, Zhejiang · NCT05279963

• PEMF therapy for women with bladder pain syndrome

  This study is testing if a new non-invasive treatment using pulsed electromagnetic fields can help women with bladder pain syndrome feel less pain and improve their urinary symptoms.

  Recruiting Wake Forest University Health Sciences · Winston-Salem, North Carolina · NCT05149573

• A program to ease pelvic pain through cognitive behavioral therapy

  This study is testing a short program of cognitive behavioral therapy to see if it can help people with chronic pelvic pain feel better compared to regular patient education.

  Recruiting State University of New York at Buffalo · Los Angeles, California and 2 other locations · NCT05127616

• Using aloe vera capsules to manage symptoms of interstitial cystitis

  This study is testing if taking aloe vera capsules can help people with interstitial cystitis feel less bladder pain and urinary frequency.

  Recruiting Early Phase 1 Wake Forest University Health Sciences · Winston-Salem, North Carolina · NCT04734106

• Identifying genetic causes of bladder pain syndrome

  This study is trying to find out if there are genetic reasons behind bladder pain syndrome by collecting DNA and health information from people who have it and their families.

  Recruiting Boston Children's Hospital · Boston, Massachusetts · NCT00389142

NIH-funded research (9)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Understanding spinal cord cell roles in bladder pain and function

  A study to map which spinal cord cells process bladder sensations and how they contribute to bladder pain and voiding problems in IC/BPS.

  NIH research Washington University · Saint Louis, United States · NIH-11386563

• How bladder support cells control the lining and bladder pain

  Researchers are exploring whether special support cells in the bladder control nerve overgrowth and damage to the bladder lining in people with interstitial cystitis/bladder pain syndrome (IC/BPS).

  NIH research Stanford University · Stanford, United States · NIH-11378890

• Personalized treatments for bladder pain (interstitial cystitis)

  A treatment approach aiming at the underlying causes of bladder pain for people with interstitial cystitis/bladder pain syndrome.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11319012

• Spinal cord cell types that drive bladder pain in interstitial cystitis (IC/BPS)

  Researchers will use precise lab tools to find which spinal cord cells cause bladder pain and troublesome urination in people with interstitial cystitis/bladder pain syndrome (IC/BPS).

  NIH research Washington University · Saint Louis, United States · NIH-11173752

• Understanding and treating bladder pain syndrome

  This study is looking at interstitial cystitis/bladder pain syndrome (IC/BPS) to find out more about different types of patients based on their symptoms, so we can create better, personalized treatments that really help with their pain and urinary issues.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11054707

• Understanding how spinal cord cells affect bladder pain and function

  This study is looking at how different types of cells in the spinal cord help process bladder pain and function in people with interstitial cystitis/bladder pain syndrome, with the hope of finding better treatments for those who suffer from this condition.

  NIH research Washington University · Saint Louis, United States · NIH-10945850

• Improving brain and muscle activity to reduce pain in women with bladder pain syndrome

  This study is looking at how brain activity affects chronic pain in women with Interstitial Cystitis/Bladder Pain Syndrome and will use a special treatment called rTMS to see if it can help improve brain and pelvic muscle function to reduce pain.

  NIH research University of Southern California · Los Angeles, UNITED STATES · NIH-10861737

• Using non-invasive electromagnetic therapy to treat bladder pain in women

  This study is looking at whether a gentle, non-invasive treatment called pulsed electromagnetic field therapy can help reduce pain for women with interstitial cystitis or bladder pain syndrome, and we're inviting 60 women to see if it really makes a difference compared to a placebo.

  NIH research Wake Forest University Health Sciences · Winston-Salem, United States · NIH-10817858

• Understanding bladder pain and its underlying causes

  This study is looking into what causes Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) in women, focusing on how certain cells in the bladder might affect pain and urinary problems, with the hope of finding better treatments for this challenging condition.

  NIH research Stanford University · Stanford, United States · NIH-10583133

Related topics

Quick answers

How many Bladder Pain Syndrome clinical trials are recruiting right now?

16, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in United States (11 trials), China (2 trials), Russia (1 trial), Turkey (Türkiye) (1 trial), Hungary (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2, Early Phase 1: 1, Phase 2/3: 1, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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