NIH-funded research R01 grant

Non-invasive imaging technique for mapping heart rhythm issues

Official title: Precision imaging of electromechanical coupling for non-invasive cardiac arrhythmia mapping

Funded at Columbia University Health Sciences · NIH-10826976 · Data updated 2026-11-12

This study is testing a new, safe imaging method called Electromechanical Wave Imaging that uses ultrasound to create a 3D picture of your heart's electrical activity, helping doctors find the cause of heart rhythm problems more easily and without any radiation.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionColumbia University Health Sciences
NIH-funded
Lab location1 site (New York, United States)
Project startSeptember 17, 2024
Project endJune 30, 2029
Funding year2024
Award (this year)$688,291
NIH project number1R01HL170606-01A1
Project IDNIH-10826976 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals aged 21 and older who are experiencing cardiac arrhythmias.

Less likely to help

Patients with stable heart conditions who do not experience arrhythmias may not benefit from this research.

What this research studies

This research focuses on developing a new non-invasive imaging technique called Electromechanical Wave Imaging (EWI) to better understand and visualize cardiac arrhythmias. By using ultrasound technology, this method aims to provide a three-dimensional view of the heart's electrical activity, which can help identify the origins of arrhythmias more accurately than traditional methods. The goal is to improve diagnosis and treatment planning for patients experiencing heart rhythm problems without exposing them to radiation or the costs associated with other imaging techniques. This innovative approach could significantly enhance the way physicians assess and manage arrhythmias.

Why it matters

Potential benefit: If successful, this research could lead to more accurate and safer diagnosis and treatment of cardiac arrhythmias, ultimately improving patient outcomes.

How similar studies have gone: Other research has shown promise with non-invasive imaging techniques for cardiac conditions, but this specific approach using EWI is relatively novel.

Where this research is happening

  • Columbia University Health Sciences
    New York, United States
    Active

Researchers

  • Principal investigator: Wan, Elaine Y — Columbia University Health Sciences
  • Study coordinator: Wan, Elaine Y

Related research

Other NIH-funded projects on the same topics.

  • Precision imaging of heart rhythms to map arrhythmias without surgery

    A new 3D ultrasound method could noninvasively map how abnormal heart rhythms start and travel, helping doctors plan safer treatments for people with arrhythmias.

    NIH research Columbia University Health Sciences · New York, United States · NIH-11385556

  • New roles for a heart protein in preventing dangerous rhythms

    A heart study will explore how a specific protein regulator (PP2A) affects ion channels that control heartbeat, with the goal of reducing dangerous arrhythmias.

    NIH research Ohio State University · Columbus, UNITED STATES · NIH-11375997

  • Understanding how small potassium channels affect heart rhythm and disease

    Aims to understand how tiny calcium-activated potassium channels influence heart rhythm and potentially lead to new treatments for atrial fibrillation and heart failure.

    NIH research University of Arizona · Tucson, United States · NIH-11294983

  • 3D ultrasound mapping to locate sources of abnormal heart rhythms

    This project uses a fast, radiation-free 3D ultrasound method to find where irregular heartbeats start in adults with arrhythmias.

    NIH research Columbia University Health Sciences · New York, United States · NIH-11193775

  • Understanding a New Way to Control Heart Rhythm Problems

    This work explores how a specific protein in the heart helps regulate electrical signals, aiming to find new ways to prevent dangerous heart rhythm issues.

    NIH research Ohio State University · Columbus, UNITED STATES · NIH-11128719

  • Exploring the mechanisms behind heart rhythm disorders

    This conference is all about helping doctors and researchers understand what causes irregular heartbeats, so they can find better ways to diagnose and treat these issues for people at risk of serious health problems like strokes or sudden heart failure.

    NIH research Gordon Research Conferences · East Greenwich, UNITED STATES · NIH-11065758

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.