Improving heart rhythm control using non-invasive techniques
Official title: Mechanistic refinement of non-invasive autonomic neuromodulation for cardiac arrhythmia
Funded at University of Pennsylvania · NIH-10915675 · Data updated 2026-11-12
This study is looking at how a special technique called repetitive transcutaneous magnetic stimulation (TcMS) can help improve heart rhythm problems, especially for people who have frequent episodes of fast heartbeats, and it aims to find new ways to manage these issues better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | September 1, 2022 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $173,340 |
| NIH project number | 5K23HL161349-03 |
| Project ID | NIH-10915675 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include patients experiencing ventricular tachycardia storms or other significant cardiac arrhythmias.
✕Less likely to help
Patients with stable heart rhythms or those who do not have arrhythmias may not benefit from this research.
What this research studies
This research investigates how the autonomic nervous system influences heart rhythm disorders, specifically cardiac arrhythmias. It explores a non-invasive method called repetitive transcutaneous magnetic stimulation (TcMS) to modulate the autonomic nervous system and improve heart function. By studying the effects of TcMS on patients experiencing ventricular tachycardia storms, the research aims to enhance our understanding of heart rhythm management and develop new treatment strategies. Patients may undergo assessments to measure the impact of this technique on their heart's electrical properties.
Why it matters
Potential benefit: If successful, this research could lead to new, effective non-invasive treatments for patients suffering from cardiac arrhythmias.
How similar studies have gone: Previous research has shown promise in using non-invasive techniques for cardiac arrhythmias, suggesting potential for success in this approach.
Where this research is happening
-
University of Pennsylvania
Philadelphia, United States Active
Researchers
- Principal investigator: Markman, Timothy — University of Pennsylvania
- Study coordinator: Markman, Timothy
Related research
Other NIH-funded projects on the same topics.
-
Precision imaging of heart rhythms to map arrhythmias without surgery
A new 3D ultrasound method could noninvasively map how abnormal heart rhythms start and travel, helping doctors plan safer treatments for people with arrhythmias.
-
New roles for a heart protein in preventing dangerous rhythms
A heart study will explore how a specific protein regulator (PP2A) affects ion channels that control heartbeat, with the goal of reducing dangerous arrhythmias.
-
Understanding how small potassium channels affect heart rhythm and disease
Aims to understand how tiny calcium-activated potassium channels influence heart rhythm and potentially lead to new treatments for atrial fibrillation and heart failure.
-
3D ultrasound mapping to locate sources of abnormal heart rhythms
This project uses a fast, radiation-free 3D ultrasound method to find where irregular heartbeats start in adults with arrhythmias.
-
Understanding a New Way to Control Heart Rhythm Problems
This work explores how a specific protein in the heart helps regulate electrical signals, aiming to find new ways to prevent dangerous heart rhythm issues.
-
Exploring the mechanisms behind heart rhythm disorders
This conference is all about helping doctors and researchers understand what causes irregular heartbeats, so they can find better ways to diagnose and treat these issues for people at risk of serious health problems like strokes or sudden heart failure.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.