Condition

Atrial Fibrillation (Paroxysmal) clinical trials and research

• 15Clinical trials
• 1New in 30 days
• 11Countries

Newest Atrial Fibrillation (Paroxysmal) clinical trials

All recruiting trials (15)

• Renal Nerve Stimulation to Help Blood Pressure in AF and HFpEF

  This study tests whether stimulating the kidneys with a catheter can safely lower blood pressure in adults with atrial fibrillation and HFpEF who also have hypertension.

  Recruiting London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · London, Ontario · NCT07893821

• Biofeedback helps people with paroxysmal atrial fibrillation stay active

  This study tests a biofeedback approach using a smartwatch to monitor AF and activity and sends personalized nudges to see if it helps people with paroxysmal AF be more physically active.

  Recruiting Liverpool John Moores University · Liverpool, Merseyside · NCT07454317

• Progressive Resistance Training First to Help AF and HFpEF Patients Feel Better

  This trial tests whether starting with progressive resistance training before aerobic exercise can improve exercise capacity and quality of life in people aged 60 and older who have atrial fibrillation and HFpEF.

  Recruiting Northwestern University · Chicago, Illinois · NCT07324772

• Digital MediYoga for quality of life and heart measures in paroxysmal atrial fibrillation

  This trial will test whether a 12-week, app-delivered MediYoga program can improve disease-specific quality of life and reduce blood pressure and heart rate in adults with paroxysmal atrial fibrillation.

  Recruiting Herlev and Gentofte Hospital · Herlev · NCT07321964

• Pulsed-field pulmonary vein isolation with optional radiofrequency nerve-targeting for paroxysmal atrial fibrillation

  This trial tests whether adding selective radiofrequency ablation of a parasympathetic ganglion to pulsed-field pulmonary vein isolation helps adults with paroxysmal atrial fibrillation have fewer recurrences and fewer bradyarrhythmic events.

  Recruiting St. Joseph's Centre, Poland · Rzeszów, Podkarpackie Voivodeship · NCT07171463

• nano-second pulsed field (nsPFA) catheter ablation for paroxysmal atrial fibrillation using the CellFX system

  The study will try the CellFX nano-second pulsed field catheter to treat adults with recurrent, drug-resistant paroxysmal atrial fibrillation.

  Recruiting Pulse Biosciences, Inc. · Prague, Roentgenova · NCT07018596

• Using a new balloon technique to treat atrial fibrillation

  This study is testing a new balloon technique to see if it can safely and effectively treat people with a type of irregular heartbeat called atrial fibrillation.

  Recruiting CardioFocus · Prague, Czech Republic · NCT06828939

• Effects of Alcohol Consumption on Atrial Fibrillation Episodes

  This study is testing whether drinking small to moderate amounts of alcohol affects how often people with paroxysmal atrial fibrillation have episodes of irregular heartbeats.

  Recruiting at 2 sites University of California, San Francisco · San Francisco, California and 1 other locations · NCT06754176

• Comparing two cryoablation techniques for treating atrial fibrillation

  This study is testing whether a larger cryoablation technique can help people with atrial fibrillation have fewer heart rhythm problems after treatment compared to a smaller technique.

  Recruiting Hospital Universitario 12 de Octubre · Pozzilli, Isernia and 16 other locations · NCT06698159

• Using a new catheter system to treat atrial fibrillation

  This study is testing a new catheter system to see if it safely helps people with paroxysmal atrial fibrillation feel better after treatment.

  Recruiting at 2 sites Pulse Biosciences, Inc. · Hasselt and 2 other locations · NCT06696170

• Comparing pulse field ablation and cryoablation for atrial fibrillation treatment

  This study is testing whether a new method called pulse field ablation works better than the traditional cryoablation for treating atrial fibrillation and keeping the heart's function healthy.

  Recruiting Assistance Publique - Hôpitaux de Paris · Paris, France · NCT06557876

• Assessing esophageal temperature during atrial fibrillation ablation

  This study is testing if a new high-power ablation method can keep the esophagus cooler and reduce injury risk during heart procedures for people with atrial fibrillation.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT06392932

• Flecainide versus amiodarone for cardioversion of recent paroxysmal atrial fibrillation in patients with treated coronary artery disease

  This study will test whether intravenous flecainide works faster and is as safe as intravenous amiodarone to restore normal rhythm in adults with recent paroxysmal atrial fibrillation who have coronary artery disease without ongoing ischemia.

  Recruiting at 3 sites Phase 3 Hippocration General Hospital · Athens and 2 other locations · NCT05549752

• Using Riluzole to Reduce Atrial Fibrillation Episodes

  This study is testing if the medication Riluzole can help reduce episodes of irregular heartbeats in adults with paroxysmal atrial fibrillation compared to a placebo.

  Recruiting Phase 2 University of Utah · Salt Lake City, Utah · NCT05292209

• Screening and treating sleep apnea in people with atrial fibrillation who are candidates for ablation

  This program will try screening for and treating sleep apnea in adults with atrial fibrillation that persists despite medication to see if treating sleep apnea lowers arrhythmia burden and reduces the need for ablation.

  Recruiting Hospital San Carlos, Madrid · Madrid, Madrid · NCT04606693

Related topics

Quick answers

How many Atrial Fibrillation (Paroxysmal) clinical trials are recruiting right now?

15, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 11 countries. The most sites are in United States (4 trials), Czechia (3 trials), Italy (2 trials), Spain (2 trials), Greece (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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